期刊
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
卷 40, 期 2, 页码 309-322出版社
WILEY
DOI: 10.1002/etc.4939
关键词
Neonicotinoid; Bumble bee; Bombus; Pesticides; Adverse outcome pathway; Ecotoxicology
资金
- Oak Ridge Institute for Science and Education
This article examines the impact of neonicotinoids on bumble bee populations and highlights the urgent need for additional studies, especially those focusing on cellular and organ responses in bumble bees exposed to neonicotinoids. Through the AOP framework, existing literature on the adverse outcome pathways is summarized, emphasizing the importance of addressing data gaps in the bumble bee research community.
Bumble bees (Bombus sp.) are important pollinators for agricultural systems and natural landscapes and have faced population declines globally in recent decades. Neonicotinoid pesticides have been implicated as one of the reasons for the population reductions in bumble bees and other pollinators due to their widespread use, specificity to the invertebrate nervous system, and toxicity to bees. Adverse outcome pathways (AOPs) are used to describe the mechanism of action of a toxicant through sequential levels of biological organization to understand the key events that occur for a given adverse outcome. We used the AOP framework to organize and present the current literature available on the impacts of neonicotinoids on bumble bees. The present review focuses on Bombus terrestris and B. impatiens, the 2 most commonly studied bumble bees due to their commercial availability. Our review does not seek to describe an AOP for the molecular initiating event shared by neonicotinoids, but rather aims to summarize the current literature and determine data gaps for the Bombus research community to address. Overall, we highlight a great need for additional studies, especially those examining cellular and organ responses in bumble bees exposed to neonicotinoids. Environ Toxicol Chem 2021;00:1-14. (c) 2020 SETAC. This article has been contributed to by US Government employees and their work is in the public domain in the USA.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据