期刊
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
卷 208, 期 -, 页码 -出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2020.111508
关键词
Air pollution; Atrial fibrillation; General population; Arrhythmia
资金
- Beijing Municipal Science and Technology Commission [Z181100001718055]
This study systematically reviewed 18 studies and found that exposure to all air pollutants had a negative impact on the prevalence of atrial fibrillation in the general population. Under short-term exposure, for every 10 μg/m3 increase in PM2.5 and PM10 concentration, the OR for AF prevalence was 1.01 and 1.03, respectively. Under long-term exposure, for every 10 μg/m3 increase in PM2.5 concentration, the OR for AF prevalence was 1.07 and for PM10 was 1.03.
Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with several risk factors. Recent studies have suggested that the exposure to air pollutants may increase the prevalence of AF, we evaluated those studies systematically to better elucidate the correlation between exposure to air pollution and AF. Method: We conducted a systematic review of publications using PubMed, Embase, the Cochrane library and Web of Science to explore the association between air pollutants and AF within the general population. The chosen studies were published until 7 July 2020. According to different study designs, we divided the outcomes into short-term-exposure group and long-term-exposure group for each pollutant. We used I-2 statistics and Q-test to examine statistical heterogeneity, and sensitivity analysis to exclude the heterogeneous study. Fixed or random-effect model was used to combine the effects. Final result was presented as the OR and 95% CI of AF prevalence for every 10 mu g/m(3) increase in the concentration of PM2.5 and PM10;10 ppb increase in the concentration of SO2 ,NO2 ,O-3; and 1 ppm increase in the CO concentration. Results: Our analysis contain 18 studies. Underlying short-term exposure effect, for each increment of 10 mu g/m3 in the PM2.5 concentration, the combined OR of AF prevalence was 1.01(1.00-1.02), for PM10 was 1.03 (1.01-1.05). For a 10 ppb increment in the concentration of SO2, NO2, and O-3 was 1.05(1.01-1.09), 1.03 (1.01-1.04), and 1.01(0.97-1.06), respectively, for a 1 ppm increase of CO concentration was 1.02(0.99-1.06). Underlying long-term-exposure effect for each increment of 10 mu g/m(3) in the PM2.5 concentration; the combined OR of AF prevalence was 1.07(1.04-1.10) and that for PM10 was 1.03(1.03-1.04) For a 10 ppb increment in the NO2 concentration was 1.02(1.00-1.04). Conclusion: Our meta-analysis indicated that all air pollutants exposure had an adverse effect on AF prevalence in general population.
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