Strontium tungstate-modified disposable strip for electrochemical detection of sulfadiazine in environmental samples

Rapid-monitoring of drugs has attracted tremendous consideration owing to robust global demand for costeffective and high effectiveness. Binary metal oxides with various morphology have been reported as electrodes for electrochemical sensor to fulfilling the clinical and enviromental requirements. In this study, strontium tungstate (SrWO4) nanoflakes have been successfully prepared via the facile sonochemical method for the first time. The characteristics of as-prepared SrWO4 are systematically measured by various analytical and spectroscopic methods. The SrWO4 nanoflakes are utilized to modify the electrochemical electrode for the sulfadiazine (SDZ) determination. The SrWO4 modified electrode possesses excellent electrocatalytic activity and high recognition capability for the electrochemical detection of SDZ. Impressively, the as-fabricated SrWO4 modified electrode attainted lowest oxidation peak at +0.93 V (vs Ag/AgCl2) with the limit of detection of 0.009 mu M, the sensitivity of 0.123 mu A mu M(-)1 cm(2) and linear detection range of 0.05-235 mu M. The enhanced performance of proposed SrWO4-based sensors could be attributed to the catalytic effect, large surface area, good electrical conductivity and physicochemical nature. Notably, the electrocatalytic performances of the SDZ sensors are good as compared to the previous literature, indicating the significance of the newly designed SrWO4 modified electrode. The real-sample diagnosis by the SDZ detection in environmental sample demonstrates the proposed SrWO4-based sensors with good recovery range.

Automated summary

In this study, SrWO4 nanoflakes were successfully prepared and used to modify an electrochemical electrode for the efficient determination of SDZ. The SrWO4 modified electrode exhibited excellent electrocatalytic activity and high recognition capability for SDZ, achieving a low oxidation peak and a wide linear detection range. The performance of the SrWO4-based sensor was enhanced due to its catalytic effect, large surface area, good electrical conductivity, and physicochemical nature, showing its significance in drug detection.