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Rishil J. Kathawala et al.
DRUG RESISTANCE UPDATES (2015)
Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure
Raymond Pagliarini et al.
EMBO REPORTS (2015)
Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism
Helena Joyce et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2015)
Identification of A Novel Small-Molecule Binding Site of the Fat Mass and Obesity Associated Protein (FTO)
Wu He et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
Amy S. Y. Lee et al.
NATURE (2015)
N6-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions
Nian Liu et al.
NATURE (2015)
m6A mRNA methylation facilitates resolution of naive pluripotency toward differentiation
Shay Geula et al.
SCIENCE (2015)
Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance
Laetitia Seguin et al.
TRENDS IN CELL BIOLOGY (2015)
A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N-6-methyladenosine demethylase FTO
Joel D. W. Toh et al.
CHEMICAL SCIENCE (2015)
Anti-inflammatory drugs and uterine cervical cancer cells: Antineoplastic effect of meclofenamic acid
Alejandro D. Soriano-Hernandez et al.
ONCOLOGY LETTERS (2015)
Meclofenamic acid selectively inhibits FTO demethylation of m(6)A over ALKBH5
Yue Huang et al.
NUCLEIC ACIDS RESEARCH (2015)
Contributions of DNA repair, cell cycle checkpoints and cell death to suppressing the DNA damage-induced tumorigenic behavior of Drosophila epithelial cells
A. Dekanty et al.
ONCOGENE (2015)
Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance
Benny Zhitomirsky et al.
ONCOTARGET (2015)
Emerging cytokine networks in colorectal cancer
Nathan R. West et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Synthesis of a FTO Inhibitor with Anticonvulsant Activity
Guanqun Zheng et al.
ACS CHEMICAL NEUROSCIENCE (2014)
m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
Pedro J. Batista et al.
CELL STEM CELL (2014)
Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N6-Methyladenosine RNA Demethylation
Chao Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Masitinib Antagonizes ATP-Binding Cassette Subfamily C Member 10-Mediated Paclitaxel Resistance: A Preclinical Study
Rishil J. Kathawala et al.
MOLECULAR CANCER THERAPEUTICS (2014)
N6-methyladenosine-dependent regulation of messenger RNA stability
Xiao Wang et al.
NATURE (2014)
Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy
Hubing Shi et al.
CANCER DISCOVERY (2014)
Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs
Rishil J. Kathawala et al.
CHINESE JOURNAL OF CANCER (2014)
Rationally designed nanovehicles to overcome cancer chemoresistance
Yoav D. Livney et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
Guanqun Zheng et al.
MOLECULAR CELL (2013)
Mutational landscape and significance across 12 major cancer types
Cyriac Kandoth et al.
NATURE (2013)
Targeting the BRAF V600E Mutation in Multiple Myeloma
Mindaugas Andrulis et al.
CANCER DISCOVERY (2013)
From tumor prevention to therapy: Empowering p53 to fight back
Christian Frezza et al.
DRUG RESISTANCE UPDATES (2012)
Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance
Nitzan Gonen et al.
DRUG RESISTANCE UPDATES (2012)
Antitumor effect of meclofenamic acid on human androgen-independent prostate cancer: a preclinical evaluation
Alejandro D. Soriano-Hernandez et al.
INTERNATIONAL UROLOGY AND NEPHROLOGY (2012)
Development of Cell-Active N6-Methyladenosine RNA Demethylase FTO Inhibitor
Baoen Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Akt Promotes Post-Irradiation Survival of Human Tumor Cells through Initiation, Progression, and Termination of DNA-PKcs-Dependent DNA Double-Strand Break Repair
Mahmoud Toulany et al.
MOLECULAR CANCER RESEARCH (2012)
Into the Eye of the Cytokine Storm
Jennifer R. Tisoncik et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2012)
Overcoming Multidrug Resistance via Photodestruction of ABCG2-Rich Extracellular Vesicles Sequestering Photosensitive Chemotherapeutics
Vicky Goler-Baron et al.
PLOS ONE (2012)
Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers
Y. Adar et al.
CELL DEATH & DISEASE (2012)
Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
Kristy J. Gotink et al.
CLINICAL CANCER RESEARCH (2011)
Nanomedicine for targeted cancer therapy: Towards the overcoming of drug resistance
Alina Shapira et al.
DRUG RESISTANCE UPDATES (2011)
The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress
S. A. Kamranvar et al.
LEUKEMIA (2011)
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
Guifang Jia et al.
NATURE CHEMICAL BIOLOGY (2011)
DNA double-strand break - induced pro-survival signaling
Amy J. Hawkins et al.
RADIOTHERAPY AND ONCOLOGY (2011)
The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis
Yehuda G. Assaraf
DRUG RESISTANCE UPDATES (2006)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)