4.7 Article

Inhibition of fatty acid synthase with FT-4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non-alcoholic fatty liver disease: Results from two early-phase randomized trials

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Chemistry, Medicinal

Recent development in acetyl-CoA carboxylase inhibitors and their potential as novel drugs

Xin Wu et al.

FUTURE MEDICINAL CHEMISTRY (2020)

Article Medicine, Research & Experimental

Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease

Gordon Smith et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Gastroenterology & Hepatology

Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation

Jamie Bates et al.

JOURNAL OF HEPATOLOGY (2020)

Article Endocrinology & Metabolism

De novo lipogenesis is essential for platelet production in humans

Kenneth L. Kelly et al.

NATURE METABOLISM (2020)

Article Endocrinology & Metabolism

Dose-dependent quantitative effects of acute fructose administration on hepatic de novo lipogenesis in healthy humans

Carine Beysen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2018)

Article Gastroenterology & Hepatology

GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease

Rohit Loomba et al.

GASTROENTEROLOGY (2018)

Article Gastroenterology & Hepatology

Association of noninvasive quantitative decline in liver fat content on MRI with histologic response in nonalcoholic steatohepatitis

Janki Patel et al.

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2016)

Article Gastroenterology & Hepatology

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

Jennifer E. Lambert et al.

GASTROENTEROLOGY (2014)

Article Biochemistry & Molecular Biology

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

Luciana Berod et al.

NATURE MEDICINE (2014)