相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。YAP1-FAM118B Fusion Defines a Rare Subset of Childhood and Young Adulthood Meningiomas
Kathleen M. Schieffer et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2021)
Prognostic stratification of clinical and molecular epithelioid hemangioendothelioma subsets
Evan Rosenbaum et al.
MODERN PATHOLOGY (2020)
YAP1-fusions in pediatric NF2-wildtype meningioma
Philipp Sievers et al.
ACTA NEUROPATHOLOGICA (2020)
Recurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-negative Sclerosing Epithelioid Fibrosarcoma
Yu-Chien Kao et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2020)
Recurrent Fusions Between YAP1 and KMT2A in Morphologically Distinct Neoplasms Within the Spectrum of Low-grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma
Florian Puls et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2020)
YAP/TAZ: Drivers of Tumor Growth, Metastasis, and Resistance to Therapy
Barry J. Thompson
BIOESSAYS (2020)
Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth
Ja Hyun Koo et al.
GENES & DEVELOPMENT (2020)
Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties
Tito Panciera et al.
NATURE MATERIALS (2020)
Yap suppresses T-cell function and infiltration in the tumor microenvironment
Eleni Stampouloglou et al.
PLOS BIOLOGY (2020)
The regulation of Yorkie, YAP and TAZ: new insights into the Hippo pathway
Samuel A. Manning et al.
DEVELOPMENT (2020)
Regulation of GPCR activation of the Hippo pathway in metastatic breast cancer
Aleena Arakaki et al.
FASEB JOURNAL (2020)
YAP1/TAZ drives ependymoma-like tumour formation in mice
Noreen Eder et al.
NATURE COMMUNICATIONS (2020)
YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response
Andriana Lebid et al.
FRONTIERS IN IMMUNOLOGY (2020)
Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis
Frank Szulzewsky et al.
GENES & DEVELOPMENT (2020)
Multimodalsingle-cellanalysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma
Jes Alexander et al.
GLIA (2020)
A Potential Role of YAP/TAZ in the Interplay Between Metastasis and Metabolic Alterations
Hirohito Yamaguchi et al.
FRONTIERS IN ONCOLOGY (2020)
Recurrent YAP1 and MAML2 Gene Rearrangements in Retiform and Composite Hemangioendothelioma
Cristina R. Antonescu et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2020)
Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine
Anwesha Dey et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer
Ethan L. Morgan et al.
PLOS PATHOGENS (2020)
Phenotypic characterization with somatic genome editing and gene transfer reveals the diverse oncogenicity of ependymoma fusion genes
Mutsumi Takadera et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2020)
Somatic Hypermutation of the YAP Oncogene in a Human Cutaneous Melanoma
Xiaomeng Zhang et al.
MOLECULAR CANCER RESEARCH (2019)
YAP/TAZ Inhibition Induces Metabolic and Signaling Rewiring Resulting in Targetable Vulnerabilities in NF2-Deficient Tumor Cells
Shannon M. White et al.
DEVELOPMENTAL CELL (2019)
Analysis of the role of the Hippo pathway in cancer
Yanyan Han
JOURNAL OF TRANSLATIONAL MEDICINE (2019)
PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice
Achira Roy et al.
ELIFE (2019)
Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma
Peiwen Chen et al.
CANCER CELL (2019)
The Emerging Role of YAP/TAZ in Tumor Immunity
Zhaoji Pan et al.
MOLECULAR CANCER RESEARCH (2019)
Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening
Gabriele Picco et al.
NATURE COMMUNICATIONS (2019)
Hippo kinase loss contributes to del(20q) hematologic malignancies through chronic innate immune activation
Samuel A. Stoner et al.
BLOOD (2019)
The Hippo Signaling Pathway in Development and Disease
Yonggang Zheng et al.
DEVELOPMENTAL CELL (2019)
Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma
Shigeki Sekine et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis
Kristian W. Pajtler et al.
NATURE COMMUNICATIONS (2019)
The Hippo Pathway: Biology and Pathophysiology
Shenghong Ma et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 88 (2019)
SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis
John M. Lamar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
miR-624-5p promoted tumorigenesis and metastasis by suppressing hippo signaling through targeting PTPRB in osteosarcoma cells
Yongjun Luo et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD•Yap Protein-Protein Interaction
Khuchtumur Bum-Erdene et al.
CELL CHEMICAL BIOLOGY (2019)
A Novel YAP1 Inhibitor Targets CSC-Enriched Radiation-Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma
Shumei Song et al.
MOLECULAR CANCER THERAPEUTICS (2018)
TumorFusions: an integrative resource for cancer-associated transcript fusions
Xin Hu et al.
NUCLEIC ACIDS RESEARCH (2018)
Cell Junctions in Hippo Signaling
Ruchan Karaman et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1
Helena J. Janse van Rensburg et al.
CANCER RESEARCH (2018)
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Francisco Sanchez-Vega et al.
CELL (2018)
Glutamine-utilizing transaminases are a metabolic vulnerability of TAZ/YAP-activated cancer cells
Chih-Sheng Yang et al.
EMBO REPORTS (2018)
The α-arrestin ARRDC3 suppresses breast carcinoma invasion by regulating G protein-coupled receptor lysosomal sorting and signaling
Aleena K. S. Arakaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell
Steven W. Plouffe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Inhibition of yes-associated protein down-regulates PD-L1 (CD274) expression in human malignant pleural mesothelioma
Ping-Chih Hsu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
YAP/TAZ upstream signals and downstream responses
Antonio Totaro et al.
NATURE CELL BIOLOGY (2018)
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD
Mengxue Yu et al.
CELL DEATH & DISEASE (2018)
miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis
Wei Kang et al.
CELL DEATH & DISEASE (2018)
Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K
Yong Suk Cho et al.
NATURE COMMUNICATIONS (2018)
YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity
Xuhao Ni et al.
CANCER DISCOVERY (2018)
YAP-Induced PD-L1 Expression Drives Immune Evasion in BRAFi-Resistant Melanoma
Min Hwan Kim et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Interplay between YAP/TAZ and Metabolism
Ja Hyun Koo et al.
CELL METABOLISM (2018)
RETRACTED ARTICLE: miR-665 promotes hepatocellular carcinoma cell migration, invasion, and proliferation by decreasing Hippo signaling through targeting PTPRB
Yuanchang Hu et al.
CELL DEATH & DISEASE (2018)
The Ambivalent Function of YAP in Apoptosis and Cancer
Xianbin Zhang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Mediated nuclear import and export of TAZ and the underlying molecular requirements
Michael Kofler et al.
NATURE COMMUNICATIONS (2018)
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
Yumeng Wang et al.
CELL REPORTS (2018)
Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation
Lucy LeBlanc et al.
ELIFE (2018)
被撤回的出版物: miR-665 promotes hepatocellular carcinoma cell migration, invasion, and proliferation by decreasing Hippo signaling through targeting PTPRB (Retracted article. See vol. 14, 2023)
Yuanchang Hu et al.
CELL DEATH & DISEASE (2018)
Inhibition of Translesion DNA Synthesis as a Novel Therapeutic Strategy to Treat Brain Cancer
Jung-Suk Choi et al.
CANCER RESEARCH (2018)
MRTF potentiates TEAD-YAP transcriptional activity causing metastasis
Tackhoon Kim et al.
EMBO JOURNAL (2017)
Crosstalk between Hippo signalling and miRNAs in tumour progression
Nianshuang Li et al.
FEBS JOURNAL (2017)
Transcriptional integration of mitogenic and mechanical signals by Myc and YAP
Ottavio Croci et al.
GENES & DEVELOPMENT (2017)
Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation
Changmin Peng et al.
MOLECULAR CELL (2017)
Hippo pathway mediates resistance to cytotoxic drugs
Taranjit S. Gujral et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ
Deanna N. Edwards et al.
SCIENCE SIGNALING (2017)
The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
Xiao Zhang et al.
NATURE COMMUNICATIONS (2017)
Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth
Chiara V. Ragni et al.
NATURE COMMUNICATIONS (2017)
YAP regulates PD-L1 expression in human NSCLC cells
Jinbai Miao et al.
ONCOTARGET (2017)
The Epithelial Circumferential Actin Belt Regulates YAP/TAZ through Nucleocytoplasmic Shuttling of Merlin
Kana T. Furukawa et al.
CELL REPORTS (2017)
The Hippo pathway in tissue homeostasis and regeneration
Yu Wang et al.
PROTEIN & CELL (2017)
The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ
Deanna N. Edwards et al.
SCIENCE SIGNALING (2017)
GPCRs: Emerging anti-cancer drug targets
Ainhoa Nieto Gutierrez et al.
CELLULAR SIGNALLING (2017)
Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex
Hung Yi Kristal Kaan et al.
SCIENTIFIC REPORTS (2017)
Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma
Erika Cosset et al.
CANCER CELL (2017)
YAP/TAZ-mediated activation of serine metabolism and methylation regulation is critical for LKB1-deficient breast cancer progression
Qi Wu et al.
BIOSCIENCE REPORTS (2017)
Src Inhibits the Hippo Tumor Suppressor Pathway through Tyrosine Phosphorylation of Lats1
Yuan Si et al.
CANCER RESEARCH (2017)
The PI3K Pathway in Human Disease
David A. Fruman et al.
CELL (2017)
YAP-1 Promotes Tregs Differentiation in Hepatocellular Carcinoma by Enhancing TGFBR2 Transcription
Ye Fan et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation
Min Hwan Kim et al.
EMBO JOURNAL (2016)
Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma
Yun-Yong Park et al.
HEPATOLOGY (2016)
Role of Merlin/NF2 inactivation in tumor biology
A. M. Petrilli et al.
ONCOGENE (2016)
Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein
M. R. Tanas et al.
ONCOGENE (2016)
Glutaminolysis as a target for cancer therapy
L. Jin et al.
ONCOGENE (2016)
YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage
E. Ciamporcero et al.
ONCOGENE (2016)
YAP Mediates Tumorigenesis in Neurofibromatosis Type 2 by Promoting Cell Survival and Proliferation through a COX-2-EGFR Signaling Axis
William Guerrant et al.
CANCER RESEARCH (2016)
Integrin signalling regulates YAP and TAZ to control skin homeostasis
Ahmed Elbediwy et al.
DEVELOPMENT (2016)
Mechanisms of Hippo pathway regulation
Zhipeng Meng et al.
GENES & DEVELOPMENT (2016)
αE-catenin inhibits a Src-YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway
Peng Li et al.
GENES & DEVELOPMENT (2016)
Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD)
Jia Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension
Thomas Bertero et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Transformation by Polyomavirus Middle T Antigen Involves a Unique Bimodal Interaction with the Hippo Effector YAP
Cecile Rouleau et al.
JOURNAL OF VIROLOGY (2016)
Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow
Li Wang et al.
NATURE (2016)
Onco-miR-130 promotes cell proliferation and migration by targeting TGFβR2 in gastric cancer
Jingjing Duan et al.
ONCOTARGET (2016)
Analysis of the hippo transducers TAZ and YAP in cervical cancer and its microenvironment
Simonetta Buglioni et al.
ONCOIMMUNOLOGY (2016)
The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN
Hiroshi Egawa et al.
SCIENTIFIC REPORTS (2016)
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
Kristian W. Pajtler et al.
CANCER CELL (2015)
YAP Promotes Malignant Progression of Lkb1-Deficient Lung Adenocarcinoma through Downstream Regulation of Survivin
Wenjing Zhang et al.
CANCER RESEARCH (2015)
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
Fa-Xing Yu et al.
CELL (2015)
The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1
Carsten Gram Hansen et al.
CELL RESEARCH (2015)
A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis
Shuying Shen et al.
CELL RESEARCH (2015)
Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Youjun Li et al.
CELL RESEARCH (2015)
The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer
Shumei Song et al.
CLINICAL CANCER RESEARCH (2015)
Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade
Yonggang Zheng et al.
DEVELOPMENTAL CELL (2015)
Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP
Qian Chen et al.
GENES & DEVELOPMENT (2015)
The Hippo pathway transcriptional co-activator, YAP, confers resistance to cisplatin in human oral squamous cell carcinoma
Kyohei Yoshikawa et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway
Nam-Gyun Kim et al.
JOURNAL OF CELL BIOLOGY (2015)
Estrogen regulates Hippo signaling via GPER in breast cancer
Xin Zhou et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Thyroid development in zebrafish lacking Taz
Andrea Pappalardo et al.
MECHANISMS OF DEVELOPMENT (2015)
Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors
Chun-Han Lin et al.
MOLECULAR BIOLOGY OF THE CELL (2015)
A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
Samantha E. Hiemer et al.
MOLECULAR CANCER RESEARCH (2015)
YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers
Giorgio G. Galli et al.
MOLECULAR CELL (2015)
A gp130-Src-YAP module links inflammation to epithelial regeneration
Koji Taniguchi et al.
NATURE (2015)
Inactivation of a Gαs-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis
Ramiro Iglesias-Bartolome et al.
NATURE CELL BIOLOGY (2015)
Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
Francesca Zanconato et al.
NATURE CELL BIOLOGY (2015)
Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy
Ajaybabu V. Pobbati et al.
STRUCTURE (2015)
YAP and TAZ: a nexus for Hippo signaling and beyond
Carsten Gram Hansen et al.
TRENDS IN CELL BIOLOGY (2015)
MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway
Zhipeng Meng et al.
NATURE COMMUNICATIONS (2015)
YAP is a critical oncogene in human cholangiocarcinoma
Tiemin Pei et al.
ONCOTARGET (2015)
Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ
Victoria Llado et al.
CELL REPORTS (2015)
YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
Claudia Stein et al.
PLOS GENETICS (2015)
A review: molecular aberrations within Hippo signaling in bone and soft-tissue sarcomas
Michael D. Deel et al.
FRONTIERS IN ONCOLOGY (2015)
The regulation and function of YAP transcription co-activator
Chu Zhu et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2015)
Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer
Tian Yu et al.
PROTEIN & CELL (2015)
Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
Marcel Kool et al.
CANCER CELL (2014)
Mutant Gq/11 Promote Uveal Melanoma Tumorigenesis by Activating YAP
Fa-Xing Yu et al.
CANCER CELL (2014)
Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
Xiaodong Feng et al.
CANCER CELL (2014)
YAP-Induced Resistance of Cancer Cells to Antitubulin Drugs Is Modulated by a Hippo-Independent Pathway
Yulei Zhao et al.
CANCER RESEARCH (2014)
YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
Luca Azzolin et al.
CELL (2014)
Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer
Avnish Kapoor et al.
CELL (2014)
Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer
Masaki Mori et al.
CELL (2014)
The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease
Xaralabos Varelas
DEVELOPMENT (2014)
The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation
Katarzyna Brodowska et al.
EXPERIMENTAL EYE RESEARCH (2014)
Pro-Invasive Activity of the Hippo Pathway Effectors YAP and TAZ in Cutaneous Melanoma
Flore Nallet-Staub et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)
Polyomavirus Small t Antigen Interacts with Yes-Associated Protein To Regulate Cell Survival and Differentiation
Justin H. Hwang et al.
JOURNAL OF VIROLOGY (2014)
Angiomotins link F-actin architecture to Hippo pathway signaling
Sebastian Mana-Capelli et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathway
Takashi Mitamura et al.
MOLECULAR CANCER (2014)
Identification, Mechanism of Action, and Antitumor Activity of a Small Molecule Inhibitor of Hippo, TGF-β, and Wnt Signaling Pathways
Dipanjan Basu et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Metabolic control of YAP and TAZ by the mevalonate pathway
Giovanni Sorrentino et al.
NATURE CELL BIOLOGY (2014)
Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers
Francesca Cottini et al.
NATURE MEDICINE (2014)
The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma
Xuelian He et al.
NATURE MEDICINE (2014)
Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration
Jonathan W. Haskins et al.
SCIENCE SIGNALING (2014)
Loss of NF2/Merlin expression in advanced sporadic colorectal cancer
Tamara Cacev et al.
CELLULAR ONCOLOGY (2014)
YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes
Erica Lorenzetto et al.
ONCOTARGET (2014)
Pax3 and Hippo Signaling Coordinate Melanocyte Gene Expression in Neural Crest
Lauren J. Manderfield et al.
CELL REPORTS (2014)
Yorkie Promotes Transcription by Recruiting a Histone Methyltransferase Complex
Hyangyee Oh et al.
CELL REPORTS (2014)
Viral Small T Oncoproteins Transform Cells by Alleviating Hippo-Pathway-Mediated Inhibition of the YAP Proto-oncogene
Hung Thanh Nguyen et al.
CELL REPORTS (2014)
The Hippo Transducer TAZ Interacts with the SWI/SNF Complex to Regulate Breast Epithelial Lineage Commitment
Adam Skibinski et al.
CELL REPORTS (2014)
The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6
Yun Qing et al.
ELIFE (2014)
Mutual interaction between YAP and c-Myc is critical for carcinogenesis in liver cancer
Weifan Xiao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2
Feng Yin et al.
CELL (2013)
Control of Nutrient Stress-Induced Metabolic Reprogramming by PKCζ in Tumorigenesis
Li Ma et al.
CELL (2013)
A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
Mariaceleste Aragona et al.
CELL (2013)
The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells
Hui Cai et al.
CELL COMMUNICATION AND SIGNALING (2013)
Regulation of Hippo Signaling by EGFR-MAPK Signaling through Ajuba Family Proteins
B. V. V. G. Reddy et al.
DEVELOPMENTAL CELL (2013)
Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma
Cristina R. Antonescu et al.
GENES CHROMOSOMES & CANCER (2013)
Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1
Run Fan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1
Ching-Wen Lin et al.
NATURE COMMUNICATIONS (2013)
Genome-wide Association of Yorkie with Chromatin and Chromatin-Remodeling Complexes
Hyangyee Oh et al.
CELL REPORTS (2013)
Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
Sangjun Lee et al.
CANCER RESEARCH (2012)
Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
Fa-Xing Yu et al.
CELL (2012)
β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
Joseph Rosenbluh et al.
CELL (2012)
A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling
Masamichi Imajo et al.
EMBO JOURNAL (2012)
Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
Jung-Soon Mo et al.
GENES & DEVELOPMENT (2012)
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
Yi Liu-Chittenden et al.
GENES & DEVELOPMENT (2012)
Function and cancer genomics of FAT family genes (Review)
Masaru Katoh
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
The N-terminal Phosphodegron Targets TAZ/WWTR1 Protein for SCFβ-TrCP-dependent Degradation in Response to Phosphatidylinositol 3-Kinase Inhibition
Wei Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Wnt/β-Catenin Signaling Regulates Yes-associated Protein (YAP) Gene Expression in Colorectal Carcinoma Cells
Wesley M. Konsavage et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
YAP mediates crosstalk between the Hippo and PI(3)K-TOR pathways by suppressing PTEN via miR-29
Karen Tumaneng et al.
NATURE CELL BIOLOGY (2012)
LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker
Dahu Chen et al.
NATURE MEDICINE (2012)
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
Georg Halder et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation
A. Fernandez-L et al.
ONCOGENE (2012)
YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes
T. Mizuno et al.
ONCOGENE (2012)
Merlin Is a Negative Regulator of Human Melanoma Growth
Lucas B. Murray et al.
PLOS ONE (2012)
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
John M. Lamar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Premetazoan Origin of the Hippo Signaling Pathway
Arnau Sebe-Pedros et al.
CELL REPORTS (2012)
YAP is a candidate oncogene for esophageal squamous cell carcinoma
Tomoki Muramatsu et al.
CARCINOGENESIS (2011)
Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation
Karin Schlegelmilch et al.
CELL (2011)
Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
Beatriz Garcia Fernandez et al.
DEVELOPMENT (2011)
Modulating F-actin organization induces organ growth by affecting the Hippo pathway
Leticia Sansores-Garcia et al.
EMBO JOURNAL (2011)
Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit
Brandon N. Nicolay et al.
GENES & DEVELOPMENT (2011)
A Novel WWTR1-CAMTA1 Gene Fusion Is a Consistent Abnormality in Epithelioid Hemangioendothelioma of Different Anatomic Sites
Costantino Errani et al.
GENES CHROMOSOMES & CANCER (2011)
Role of YAP/TAZ in mechanotransduction
Sirio Dupont et al.
NATURE (2011)
E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components
Nam-Gyun Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size
Todd Heallen et al.
SCIENCE (2011)
α-Catenin Is a Tumor Suppressor That Controls Cell Accumulation by Regulating the Localization and Activity of the Transcriptional Coactivator Yap1
Mark R. Silvis et al.
SCIENCE SIGNALING (2011)
Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma
Munir R. Tanas et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
LATS tumor suppressor A new governor of cellular homeostasis
Stacy Visser et al.
CELL CYCLE (2010)
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms
Fangfang Ren et al.
DEVELOPMENTAL BIOLOGY (2010)
The Hippo Pathway Regulates Wnt/β-Catenin Signaling
Xaralabos Varelas et al.
DEVELOPMENTAL CELL (2010)
The Hippo Signaling Pathway in Development and Cancer
Duojia Pan
DEVELOPMENTAL CELL (2010)
The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway
Xaralabos Varelas et al.
DEVELOPMENTAL CELL (2010)
Structural basis of YAP recognition by TEAD4 in the Hippo pathway
Liming Chen et al.
GENES & DEVELOPMENT (2010)
Structural insights into the YAP and TEAD complex
Ze Li et al.
GENES & DEVELOPMENT (2010)
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
Bin Zhao et al.
GENES & DEVELOPMENT (2010)
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF beta-TRCP
Bin Zhao et al.
GENES & DEVELOPMENT (2010)
The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase
Chen-Ying Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
Xi Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Mutations in GNA11 in Uveal Melanoma.
Catherine D. Van Raamsdonk et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene 'FAT' in human astrocytic tumors
Kunzang Chosdol et al.
BMC CANCER (2009)
Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZ-binding motif
Tsutomu Oka et al.
GENES TO CELLS (2009)
TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition
Heng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Structure-Activity Relationship Studies of Fostriecin, Cytostatin, and Key Analogs, with PP1, PP2A, PP5, and (β12-β13)-Chimeras (PP1/PP2A and PP5/PP2A), Provide Further Insight into the Inhibitory Actions of Fostriecin Family Inhibitors
Mark R. Swingle et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
PAR1 is selectively over expressed in high grade breast cancer patients: a cohort study
Norma A. Hernandez et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2009)
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
Catherine D. Van Raamsdonk et al.
NATURE (2009)
Yes-associated protein (YAP) functions as a tumor suppressor in breast
M. Yuan et al.
CELL DEATH AND DIFFERENTIATION (2008)
MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
Maria Praskova et al.
CURRENT BIOLOGY (2008)
In vivo regulation of Yorkie phosphorylation and localization
Hyangyee Oh et al.
DEVELOPMENT (2008)
TEAD mediates YAP-dependent gene induction and growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2008)
Cell polarity and cancer - cell and tissue polarity as a non-canonical tumor suppressor
Minhui Lee et al.
JOURNAL OF CELL SCIENCE (2008)
Yap1 phosphorylation by c-AbI is a critical step in selective activation of proapoptotic genes in response to DNA damage
Dan Levy et al.
MOLECULAR CELL (2008)
Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation
Maria Willecke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Inactivation of the NF2 tumor suppressor protein merlin in DU145 prostate cancer cells
Akio Horiguchi et al.
PROSTATE (2008)
Clonal integration of a polyomavirus in human Merkel cell carcinoma
Huichen Feng et al.
SCIENCE (2008)
Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ
Ryosuke Makita et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
YAP1 increases organ size and expands undifferentiated progenitor cells
Fernando D. Camargo et al.
CURRENT BIOLOGY (2007)
The genomic landscapes of human breast and colorectal cancers
Laura D. Wood et al.
SCIENCE (2007)
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2007)
Elucidation of a universal size-control mechanism in Drosophila and mammals
Jixin Dong et al.
CELL (2007)
Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array
K. Nakaya et al.
ONCOGENE (2007)
Mutational spectrum of the NF2 gene:: A meta-analyslis of 12 years of research and diagnostic laboratory findings
Iris Ahronowitz et al.
HUMAN MUTATION (2007)
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73
D. Levy et al.
CELL DEATH AND DIFFERENTIATION (2007)
The tumor-suppressor gene fat controls tissue growth upstream of expanded in the Hippo signaling pathway
Elizabeth Silva et al.
CURRENT BIOLOGY (2006)
The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size
Maria Willecke et al.
CURRENT BIOLOGY (2006)
The consensus coding sequences of human breast and colorectal cancers
Tobias Sjoeblom et al.
SCIENCE (2006)
The human tumour suppressor LATS1 is activated by human MOB1 at the membrane
Alexander Hergovich et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65
EM Morin-Kensicki et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation
JH Hong et al.
SCIENCE (2005)
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP
JB Huang et al.
CELL (2005)
The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA damage
S Strano et al.
MOLECULAR CELL (2005)
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
EH Chan et al.
ONCOGENE (2005)
Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level
J Omerovic et al.
EXPERIMENTAL CELL RESEARCH (2004)
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
JH Jia et al.
GENES & DEVELOPMENT (2003)
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
RS Udan et al.
NATURE CELL BIOLOGY (2003)
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
A Komuro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
KF Harvey et al.
CELL (2003)
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
S Wu et al.
CELL (2003)
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
S Basu et al.
MOLECULAR CELL (2003)
salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
N Tapon et al.
CELL (2002)
Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-β/Smad signaling
O Ferrigno et al.
ONCOGENE (2002)
Neurofibromatosis 2 and malignant mesothelioma
ME Baser et al.
NEUROLOGY (2002)
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
A Vassilev et al.
GENES & DEVELOPMENT (2001)
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
S Strano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
F Kanai et al.
EMBO JOURNAL (2000)
分享论文
