Chlorogenic Acid Improves PTSD-like Symptoms and Associated Mech-anisms

Chlorogenic acid (CGA) is a kind of traditional Chinese medicine, abundant in honey-suckle and eucommia, and has a wide range of biological activities, and pharmacological effects. Previous studies have shown that CGA can regulate learning, memory, cognitive ability, coupled with improvement to anxiety, depression, and other post-traumatic stress disorder (PTSD)-like symptoms. This article explores the protective effects of CGA on neurons through its anti-apoptot-ic effect, inhibition of neuroinflammation and oxidative stress, which may be the mechanisms of its improvement of PTSD-like symptoms. It may provide a new therapeutic strategy for the treat-ment of PTSD and its comorbidities.

Automated summary

Chlorogenic acid, a traditional Chinese medicine found in honey-suckle and eucommia, has been shown to regulate learning, memory, cognitive ability, and improve symptoms of anxiety, depression, and PTSD-like symptoms. It may provide a new therapeutic strategy for the treatment of PTSD and its comorbidities.