Advances in Biomedical Application of Nanocelulose-Based Materials: A Review

Background: Recently, there has been increasing interest in nanomaterials processed using renewable and sustainable resources. Nanocellulose-based materials are of paramount value in the applications of biomedicine owing to their tailorable surface modification, favorable optical transparency, good hydrophilicity, excellent biocompatibility, and outstanding mechanical properties. Objective: In the review, the recent advancements of nanocellulose, including cellulose nanofibers (CNFs), cellulose nanocrystals (CNCs), and bacterial cellulose (BC), are summarized, which are promising for biomedical applications. Results: By discussing different forms (one-dimensional (1D), two-dimensional (2D), and three-dimensional (3D)), the superiority of the nanocellulose-based materials with different constructed structures will be clarified for various biomedical applications, such as biosensing, drug delivery, wound dressing, and tissue engineering. Conclusion: The challenges and prospects for the future development of nanocellulose-based materials in biomedical applications are also discussed at the end of the review.

Automated summary

This article summarizes recent advances in nanocellulose, including cellulose nanofibers (CNFs), cellulose nanocrystals (CNCs), and bacterial cellulose (BC), which are promising for biomedical applications. The superiority of nanocellulose-based materials with different constructed structures for various biomedical applications such as biosensing, drug delivery, wound dressing, and tissue engineering is discussed. Challenges and prospects for the future development of nanocellulose-based materials in biomedical applications are also addressed.