Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review

The prostate-specific antigen (PSA) has been considered a crucial serological marker for distinguishing prostate based cancer. This survey shows recent progress in the construction of nanomaterial-based electrochemical immunosensors for a PSA. This review (from 2015 to 2020) reports the latest progress in PSA sensing based on the employ of different types of nanostructured materials. The most popular used nanostructured materials are metal, metal oxide, carbon-based nanomaterials, and their hybrid architectures utilized for distinct amplification protocols. In this review, the electrochemical immunosensors for prostate- specific antigen sensing are classified into three categories such as sandwich type@labeled, label free@nonlabeled and aptamer-based electrochemical immunosensor.

Automated summary

This review summarizes recent progress in constructing nanomaterial-based electrochemical immunosensors for prostate-specific antigen (PSA), with a focus on the use of metal, metal oxide, and carbon-based nanomaterials, as well as hybrid architectures for amplification of signals. The review classifies the electrochemical immunosensors for PSA sensing into three categories: sandwich type labeled, label-free non-labeled, and aptamer-based sensors.