期刊
CLINICAL NUCLEAR MEDICINE
卷 46, 期 1, 页码 49-51出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLU.0000000000003400
关键词
cricoid cartilage; duodenum adenocarcinoma; FDG; PCa; PSMA-1007
A 76-year-old man with dyspnea and initial prostate-specific antigen of 216 ng/mL was diagnosed with prostate cancer. Despite initial therapy, he later developed castration-resistant state with additional tumors detected. The use of PET/CT scans revealed metastasis to T5 vertebra and duodenum.
A 76-year-old man with dyspnea (initial prostate-specific antigen [PSA]: 216 ng/mL) underwent F-18-FDG PET/CT, with uptake in the prostate, lymph nodes, fifth thoracic vertebra (T5), and cricoid cartilage. A biopsy revealed prostate adenocarcinoma (Gleason score 4 + 5, cT4 N1 M1). On initiation of combined androgen blockade therapy, PSA value decreased. However, 4 years later, in a castration-resistant state (PSA 2.14 ng/mL), CT and bone scintigraphy revealed a duodenal tumor and T5 metastasis. F-18-prostate-specific membrane antigen-1007 PET/CT showed uptake in the already known T5 metastasis (SUVmax, 33.55) and even in the duodenal tumor (16.55). The latter was histologically diagnosed as duodenal adenocarcinoma.
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