Previous Dengue Infection and Mortality in Coronavirus Disease 2019 (COVID-19)

We studied 2351 participants with coronavirus disease 2019; 1177 (50%) reported previous dengue infection. Those without previous dengue had a higher risk of death (hazard ratio: .44; 95% confidence interval: .22-.89; P = .023) in 60-day follow-up. These findings raise the possibility that dengue might induce immunological protection against severe acute respiratory syndrome coronavirus 2.

Automated summary

The study showed that COVID-19 patients with no history of dengue infection had a higher risk of death in the 60-day follow-up, indicating the potential immunological protection effect of dengue against severe acute respiratory syndrome coronavirus 2.