4.7 Article

Predicting CAR-T cell Immunotherapy Success through ImmunoPET

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CLINICAL CANCER RESEARCH
卷 27, 期 4, 页码 911-912

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AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1078-0432.CCR-20-4297

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  1. NCI [CA204924, R35 CA232130, P30 CA08748]

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CAR-T cell therapy has made unprecedented advances in treating hematologic cancers, but there is a lack of readily translatable imaging approaches to visualize the dynamics of CAR-T cells in vivo. Noninvasive PET imaging is considered the ideal tool for monitoring CAR-T cells.
Chimeric antigen receptor (CAR)-T cell therapy has generated unprecedented advances in the treatment of hematologic cancers, but readily translatable imaging approaches to visualize the in vivo dynamics of CAR-T cells are lacking. Noninvasive PET imaging is the ideal tool to monitor CAR-T cells.

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