期刊
CHINESE JOURNAL OF CHEMISTRY
卷 39, 期 4, 页码 913-917出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.202000579
关键词
Acrylonitriles; Nucleophilic substitution; Isomerization; α ‐ Cyanohydrin methanesulfonates; Alkenyl boronic acids
This study presents an efficient synthesis of acrylonitriles via a mild and transition metal-free protocol with good chemical yields for a wide range of substrates and good functional group tolerance.
Main observation and conclusion We have developed an efficient synthesis of acrylonitriles via mild base promoted tandem nucleophilic substitution-isomerization of alpha-cyanohydrin methanesulfonates with alkenylboronic acids. This transition metal-free protocol works under simple and mild conditions and offers good chemical yields for a wide range of substrates and demonstrates good functional group tolerance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据