期刊
CHEMISTRY LETTERS
卷 50, 期 4, 页码 580-584出版社
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.200866
关键词
Protein-protein interaction; Hybridization; Aplyronine A
This review discusses recent progress in the design of artificial analogs of Aplyronine A, including hybridization and structure-activity relationship studies, to further understand its novel mode of action as an antitumor marine macrolide inducing protein-protein interaction between actin and tubulin.
Aplyronine A, an antitumor marine macrolide, has a novel mode of action, inducing the protein-protein interaction between two major cytoskeletons, actin and tubulin. This review discusses recent progress in the design of artificial analogs including hybridization and structure-activity relationship studies of aplyronine A.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据