Fabrication of Magnesium oxide nanoparticles using combustion method for a biological and environmental cause

Magnesium Oxide (MgO) nanoparticles represent one of the promising classes of nanomaterials owing to their lightweight property, biocompatibility, and rapid metabolic activity. Nanomaterials with such characteristics had been the most sought-after alternative to heavy metals for application in photodynamic and cancer therapy. The prime focus of this study is to investigate the toxicity and catalytic activity of morphologically different MgO NPs obtained by various fuel ratios. The synthesized MgO was characterized using UV-visible spectroscopy, X-ray diffraction, Fourier Transform-Infrared spectroscopy, and electron microscopic studies. The toxicity dependent parameters were evaluated using clinically significant Staphylococcus aureus (S. aureus) and Escherichia toll (E. coli) models. The feasibility of appending MgO for the photocatalytic effect was assessed using rhodamine dye. The maximum absorbance was obtained with a prominent peak absorbance were observed by UV-vis spectra. The corresponding band gap for MgO NPs was calculated using Tauc's plot. From the X-ray diffraction (XRD) analysis, the MgO NPs are found to have formed in a face-centric cubic structure. The FTIR spectra confirms the successful formation of MgO NPs. The morphological analysis indicated the flakes-like structures and EDX for the elemental composition. There was a significant antibacterial effect on the tested strains at 10 mu g/mL concentration as determined by MIC. The dye degradation efficiency of MgO was found significant in the presence of artificial light accomplished within 180 min of irradiating rhodamine dye.

Automated summary

This study focuses on investigating the toxicity and catalytic activity of morphologically different MgO nanoparticles, synthesized using various fuel ratios, through characterization techniques and evaluation with bacterial models such as Staphylococcus aureus and Escherichia coli. The results show promising antibacterial effects and significant dye degradation efficiency of MgO nanoparticles under artificial light.