n-Butyllithium Catalyzed Hydroboration of Nitriles and Carbodiimides

Highly efficient and selective hydroboration of nitriles and carbodiimides with pinacolborane (HBpin) is achieved by using the simple and convenient n-BuLi as a catalyst. Solvent-free and good functional group tolerance under mild conditions have been achieved. A possible mechanistic pathway of the n-BuLi catalyzed hydroboration of nitriles with HBpin is proposed.

Automated summary

The study demonstrates highly efficient and selective hydroboration of nitriles and carbodiimides using n-BuLi as a catalyst with pinacolborane. The reaction shows good functional group tolerance and can be carried out solvent-free under mild conditions. A possible mechanistic pathway for the n-BuLi catalyzed hydroboration of nitriles with HBpin is proposed.