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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Trim24 targets endogenous p53 for degradation
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator
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Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes
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CELL (2008)
Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase
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EUROPEAN JOURNAL OF HUMAN GENETICS (2008)
Fragment approaches in structure-based drug discovery
Roderick E. Hubbard
JOURNAL OF SYNCHROTRON RADIATION (2008)
PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing
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MOLECULAR CELL (2007)
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Unique features of TRIM5α among closely related human TRIM family members
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VIROLOGY (2007)
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MOLECULAR IMMUNOLOGY (2007)
The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity
Masha V. Poyurovsky et al.
EMBO JOURNAL (2007)
Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos
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CURRENT BIOLOGY (2006)
Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53
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JOURNAL OF MOLECULAR BIOLOGY (2006)
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EMBO JOURNAL (2006)
Solution structure of the RBCC/TRIM B-box1 domain of human MlDl: B-box with a RING
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JOURNAL OF MOLECULAR BIOLOGY (2006)
A tandem affinity tag for two-step purification under fully denaturing conditions -: Application in ubiquitin profiling and protein complex identification combined with in vivo cross-linking
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MOLECULAR & CELLULAR PROTEOMICS (2006)
The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Structure of the PRYSPRY-domain:: Implications for autoinflammatory diseases
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FEBS LETTERS (2006)
Relationship between SPRY and B30.2 protein domains. Evolution of a component of immune defence?
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IMMUNOLOGY (2005)
TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
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BIOESSAYS (2005)
Function and regulation of Cullin-RING ubiquitin ligases
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
N-terminal ubiquitination: more protein substrates join in
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TRENDS IN CELL BIOLOGY (2004)
Model of the Brain Tumor-Pumilio translation repressor complex
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GENES & DEVELOPMENT (2003)
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NATURE (2003)
MID1 and MID2 homo- and hetero-dimerise to tether the rapamycin-sensitive PP2A regulatory subunit, Alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders
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BMC CELL BIOLOGY (2002)
Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene
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AMERICAN JOURNAL OF HUMAN GENETICS (2002)
PML protein isoforms and the RBCC/TRIM motif
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ONCOGENE (2001)
Proteasome inhibitors: from research tools to drug candidates
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Structural basis of IAP recognition by Smac/DIABLO
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