Hierarchical Pt-decorated In2O3 microspheres with highly enhanced isoprene sensing properties

For advanced fibrosis, isoprene is a typical characteristic marker that could be used to quickly screen the population for chronic liver disease (CLD). To achieve trace detection of isoprene, different mol% Pt-decorated In2O3 and pure In2O3 samples were prepared with the commonly used hydrothermal method. The obtained characterization results show that the prepared Pt-decorated In2O3 (1 mol%) sample had Pt nanoparticles uniformly attached to the surface of porous hierarchical In2O3 nanosheets, and the specific surface area was 62.3 m(2)/g. Subsequently, these sensors based on Pt-In2O3 and pure In2O3 nanomaterials were prepared, and their response characteristics were studied. The results show that the response of 1 mol% Pt-In2O3 to isoprene gas was significantly enhanced, and the optimal working temperature was 200 degrees C. The response of 1 mol% Pt-In2O3 to 5 ppb and 5 ppm isoprene was approximately 3.2 times and 25.9 times that of pure In2O3, respectively. Meanwhile, the 1 mol% Pt-modified sample exhibited excellent selectivity for isoprene relative to other biomarkers (carbon monoxide, hydrogen, ethanol, and ammonia). The sensor shows good repeatability and long-term stability. Therefore, the developed 1 mol% Pt-decorated In2O3 was expected to be applied as a gas-sensitive material for breath isoprene, which could be suitable for large-scale CLD rapid breath detection.

Automated summary

The research indicates that 1 mol% Pt-decorated In2O3 shows significantly enhanced response to isoprene gas, with good selectivity, repeatability, and long-term stability, making it suitable for large-scale rapid breath detection of chronic liver disease.