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Hiromi Abe et al.
INTERNATIONAL IMMUNOLOGY (2014)
Characterization of the CD40L/Oncostatin M/Oncostatin M receptor axis as an antiviral and immunostimulatory system disrupted in chronic HCV infection
Esther Larrea et al.
JOURNAL OF HEPATOLOGY (2014)
Intrahepatic regulatory T cells in autoimmune hepatitis are associated with treatment response and depleted with current therapies
Richard Taubert et al.
JOURNAL OF HEPATOLOGY (2014)
IL-27, a Cytokine, and IFN-λ1, a Type III IFN, Are Coordinated To Regulate Virus Replication through Type I IFN
Yanhua Cao et al.
JOURNAL OF IMMUNOLOGY (2014)
Acute and Chronic Effects of IL-22 on Acetaminophen-Induced Liver Injury
Dechun Feng et al.
JOURNAL OF IMMUNOLOGY (2014)
Therapeutic opportunities of the IL-22-IL-22R1 system
Robert Sabat et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Human but Not Mouse Hepatocytes Respond to Interferon-Lambda In Vivo
Pascale Hermant et al.
PLOS ONE (2014)
Synthesis of IL-6 by Hepatocytes Is a Normal Response to Common Hepatic Stimuli
Callie A. Norris et al.
PLOS ONE (2014)
Mechanisms of tissue injury in autoimmune liver diseases
Evaggelia Liaskou et al.
SEMINARS IN IMMUNOPATHOLOGY (2014)
IL-37 protects against obesity-induced inflammation and insulin resistance
Dov B. Ballak et al.
NATURE COMMUNICATIONS (2014)
Application of Interleukin-22 Mediates Protection in Experimental Acetaminophen-Induced Acute Liver Injury
Patrick Scheiermann et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Interleukin-33-Dependent Innate Lymphoid Cells Mediate Hepatic Fibrosis
Tamar Mchedlidze et al.
IMMUNITY (2013)
Interleukin-19 Mediates Tissue Damage in Murine Ischemic Acute Kidney Injury
Yu-Hsiang Hsu et al.
PLOS ONE (2013)
Eosinophils secrete IL-4 to facilitate liver regeneration
Y. P. Sharon Goh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease
Amina A. Negash et al.
PLOS PATHOGENS (2013)
Human Schistosomiasis: Clinical Perspective: Review
Rashad S. Barsoum et al.
JOURNAL OF ADVANCED RESEARCH (2013)
Gene-viro-therapy targeting liver cancer by a dual-regulated oncolytic adenoviral vector harboring IL-24 and TRAIL
X. Liu et al.
CANCER GENE THERAPY (2012)
Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor
N. A. Molfino et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2012)
Interleukin (IL)-17/IL-22-Producing T cells Enriched Within the Liver of Patients with Chronic Hepatitis C Viral (HCV) Infection
Richard G. Foster et al.
DIGESTIVE DISEASES AND SCIENCES (2012)
Interleukin-22 Promotes Proliferation of Liver Stem/Progenitor Cells in Mice and Patients With Chronic Hepatitis B Virus Infection
Dechun Feng et al.
GASTROENTEROLOGY (2012)
Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice
Fanli Meng et al.
GASTROENTEROLOGY (2012)
Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
Wolfgang Hueber et al.
GUT (2012)
TRAIL But Not FasL and TNFα, Regulates IL-33 Expression in Murine Hepatocytes During Acute Hepatitis
Muhammad Imran Arshad et al.
HEPATOLOGY (2012)
Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice
Xiaoni Kong et al.
HEPATOLOGY (2012)
Amazing IL-9: revealing a new function for an old cytokine
Edgar Schmitt et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Th9 cells promote antitumor immune responses in vivo
Yong Lu et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
Jan Petrasek et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Th17 cells are increased with severity of liver inflammation in patients with chronic hepatitis C
Qing Chang et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2012)
Role of Hepatocyte-Derived IL-7 in Maintenance of Intrahepatic NKT Cells and T Cells and Development of B Cells in Fetal Liver
Bingfei Liang et al.
JOURNAL OF IMMUNOLOGY (2012)
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
Jorge Henao-Mejia et al.
NATURE (2012)
Interleukin-11 Links Oxidative Stress and Compensatory Proliferation
Takashi Nishina et al.
SCIENCE SIGNALING (2012)
Hepatoprotective effects of IL-22 on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice
Wei-Wei Xing et al.
CYTOKINE (2011)
A Proinflammatory Role for Interleukin-22 in the Immune Response to Hepatitis B Virus
Ye Zhang et al.
GASTROENTEROLOGY (2011)
Inflammation-Associated Interleukin-6/Signal Transducer and Activator of Transcription 3 Activation Ameliorates Alcoholic and Nonalcoholic Fatty Liver Diseases in Interleukin-10-Deficient Mice
Andrew M. Miller et al.
HEPATOLOGY (2011)
Interleukin-22 Promotes Human Hepatocellular Carcinoma by Activation of STAT3
Runqiu Jiang et al.
HEPATOLOGY (2011)
In Vivo Consequences of Liver-Specific Interleukin-22 Expression in Mice: Implications for Human Liver Disease Progression
Ogyi Park et al.
HEPATOLOGY (2011)
Functional Specialization of Interleukin-17 Family Members
Yoichiro Iwakura et al.
IMMUNITY (2011)
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
Simon A. Jones et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
Yehuda Kamari et al.
JOURNAL OF HEPATOLOGY (2011)
Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand
Laura A. Solt et al.
NATURE (2011)
Th17 cells and their associated cytokines in liver diseases
Fouad Lafdil et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2010)
IL-10 family of cytokines
Robert Sabat
CYTOKINE & GROWTH FACTOR REVIEWS (2010)
Interleukin-17-Producing CD4(+) T Cells Increase with Severity of Liver Damage in Patients with Chronic Hepatitis B
Ji-Yuan Zhang et al.
HEPATOLOGY (2010)
Interleukin-6 Is an Important Mediator for Mitochondrial DNA Repair After Alcoholic Liver Injury in Mice
Xiuying Zhang et al.
HEPATOLOGY (2010)
Interleukin-22 Treatment Ameliorates Alcoholic Liver Injury in a Murine Model of Chronic-Binge Ethanol Feeding: Role off Signal Transducer and Activator of Transcription 3
Sung Hwan Ki et al.
HEPATOLOGY (2010)
Alternative Activation of Macrophages: Mechanism and Functions
Siamon Gordon et al.
IMMUNITY (2010)
Interleukin-33 overexpression is associated with liver fibrosis in mice and humans
Pierrick Marvie et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)
Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22
Ling Yang et al.
JOURNAL OF HEPATOLOGY (2010)
IL-22 Induces an Acute-Phase Response
Spencer C. Liang et al.
JOURNAL OF IMMUNOLOGY (2010)
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
Kajsa Wing et al.
NATURE IMMUNOLOGY (2010)
Interleukin-1 participates in the progression from liver injury to fibrosis
Roben G. Gieling et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been
Timothy F. Osborne et al.
GENES & DEVELOPMENT (2009)
The Interleukin-17 Pathway Is Involved in Human Alcoholic Liver Disease
Arnaud Lemmers et al.
HEPATOLOGY (2009)
Hepatic Interleukin-7 Expression Regulates T Cell Responses
Yukihisa Sawa et al.
IMMUNITY (2009)
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22
Hiroaki Takatori et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
IL-9 as a mediator of Th17-driven inflammatory disease
Elizabeth C. Nowak et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes
Anneli Jaeger et al.
JOURNAL OF IMMUNOLOGY (2009)
IL-17A Controls IL-17F Production and Maintains Blood Neutrophil Counts in Mice
Sibylle von Vietinghoff et al.
JOURNAL OF IMMUNOLOGY (2009)
IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells
Caroline Diveu et al.
JOURNAL OF IMMUNOLOGY (2009)
IL-22-Dependent Attenuation of T Cell-Dependent (ConA) Hepatitis in Herpes Virus Entry Mediator Deficiency
Christian Wahl et al.
JOURNAL OF IMMUNOLOGY (2009)
IL-6 Deficiency Attenuates Murine Diet-Induced Non-Alcoholic Steatohepatitis
Emmanuel Mas et al.
PLOS ONE (2009)
IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells
Wassim Elyaman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structure and signalling in the IL-17 receptor family
Sarah L. Gaffen
NATURE REVIEWS IMMUNOLOGY (2009)
The role of interleukin-22 in hepatitis C virus infection
Julia Dambacher et al.
CYTOKINE (2008)
A Randomized, Double-Blinded, Placebo-Controlled Multicenter Trial of Etanercept in the Treatment of Alcoholic Hepatitis
Nicholas C. Boetticher et al.
GASTROENTEROLOGY (2008)
Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities
Erika A. Rickel et al.
JOURNAL OF IMMUNOLOGY (2008)
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
Yan Zheng et al.
NATURE MEDICINE (2008)
Cellular cholesterol trafficking and compartmentalization
Elina Ikonen
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
IL-13 receptor alpha 2 selectively inhibits IL-13-induced responses in the murine lung
Tao Zheng et al.
JOURNAL OF IMMUNOLOGY (2008)
IL-17B and IL-17C are associated with TNF-α production and contribute to the exacerbation of inflammatory arthritis
Yumi Yamaguchi et al.
JOURNAL OF IMMUNOLOGY (2007)
Interleukin-22 but not interleukin-17 provides protection to Hepatocytes during acute liver inflammation
Lauren A. Zenewicz et al.
IMMUNITY (2007)
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
Claus M. Larsen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice
Hongwei Yu et al.
BMC DEVELOPMENTAL BIOLOGY (2007)
IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro
Stephan Brand et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
The murine liver is a potential target organ for IL-19, IL-20 and IL-24: Type I Interferons and LPS regulate the expression of IL-20R2
Ursula Maria Wegenka et al.
JOURNAL OF HEPATOLOGY (2007)
IFN-γ abrogates profibrogenic TGF-β signaling in liver by targeting expression of inhibitory and receptor Smads
Honglei Weng et al.
JOURNAL OF HEPATOLOGY (2007)
IL-25 regulates Th17 function in autoimmune inflammation
Melanie A. Kleinschek et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity
Won-Il Jeong et al.
HEPATOLOGY (2006)
Interferons, immunity and cancer immunoediting
Gavin P. Dunn et al.
NATURE REVIEWS IMMUNOLOGY (2006)
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
Ivaylo I. Ivanov et al.
CELL (2006)
Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners
S Radaeva et al.
GASTROENTEROLOGY (2006)
IL-13 signaling through the IL-13 alpha 2 receptor is involved in induction of TGF-beta 1 production and fibrosis
S Fichtner-Feigl et al.
NATURE MEDICINE (2006)
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
J Schmitz et al.
IMMUNITY (2005)
IL-24 inhibits the growth of hepatoma cells in vivo
WY Chen et al.
GENES AND IMMUNITY (2005)
Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression
HW Yu et al.
DEVELOPMENTAL BRAIN RESEARCH (2005)
Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): Biologic outcome in advanced cancer patients
AW Tong et al.
MOLECULAR THERAPY (2005)
Clinical and local biological effects of an intraturnoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study
CC Cunningham et al.
MOLECULAR THERAPY (2005)
The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains
S Hör et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
S Radaeva et al.
HEPATOLOGY (2004)
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
DJ Cua et al.
NATURE (2003)
Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line - Pathways that are shared with and distinct from IL-10
D Lejeune et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
IL-17 selectively down-regulates TNF-α-induced RANTES gene expression in human colonic subepithelial myofibroblasts
A Andoh et al.
JOURNAL OF IMMUNOLOGY (2002)
Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis
T Starnes et al.
JOURNAL OF IMMUNOLOGY (2002)
The immunobiology of schistosomiasis
EJ Pearce et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Cutting edge: Immune cells as sources and targets of the IL-10 family members?
K Wolk et al.
JOURNAL OF IMMUNOLOGY (2002)
Interferon-α activates multiple STAT signals and downregulates c-Met in primary human hepatocytes
S Radaeva et al.
GASTROENTEROLOGY (2002)
Expression of IL-17B in neurons and evaluation of its possible role in the chromosome 5q-linked form of Charcot-Marie-Tooth disease
EE Moore et al.
NEUROMUSCULAR DISORDERS (2002)
7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome
BU Fitzky et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Interleukin 20: Discovery, receptor identification, and role in epidermal function
H Blumberg et al.
CELL (2001)
IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1
J Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development
MJ Townsend et al.
IMMUNITY (2000)
Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri
A Knappe et al.
JOURNAL OF VIROLOGY (2000)
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
WJ Ouyang et al.
IMMUNITY (2000)
Fas- and tumor necrosis factor receptor 1-dependent but not perforin-dependent pathways cause injury in livers infected with an adenovirus construct in mice
ZX Liu et al.
HEPATOLOGY (2000)
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