期刊
CARBOHYDRATE POLYMERS
卷 252, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2020.117176
关键词
Encapsulation; Hydrophobically modified inulin; Controlled release; Emulsions; Gut microbiota
资金
- National Key Research and Development Program of China [2017YFD0400206]
The hydrophobically modified inulin (HMI) has gained attention for its multiple features. The review discusses the limitations of SCFAs inulin esters, real food dispersion formulations, and HMI drugs. The results show the potential of HMI as an excipient for hydrophobic drugs.
Over the past few years, hydrophobically modified inulin (HMI) has gained considerable attention due to its multitudinous features. The targeted release of drugs remains a subject of research interest. Moreover, it is important to explore the properties of short-chain fatty acids (SCFAs) inulin esters because they are less studied. Additionally, HMI has been used to stabilize various dispersion formulations, which have been observed to be safe because inulin is generally recognized as safe (GRAS). However, the results regarding HMI-based dispersion products are dispersed throughout the literature. This comprehensive review is discussed the possible limitations regarding SCFAs inulin esters, real food dispersion formulations, and HMI drugs. The results revealed that SCFAs inulin esters can regulate the human gut microbiota and increase the biological half-life of SCFAs in the human body. This comprehensive review discusses the versatility of HMI as a promising excipient for the production of hydrophobic drugs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据