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Omomyc Reveals New Mechanisms To Inhibit the MYC Oncogene
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Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer
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Inhibiting MYC binding to the E-box DNA motif by ME47 decreases tumour xenograft growth
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ONCOGENE (2017)
MB0 and MBI Are Independent and Distinct Transactivation Domains in MYC that Are Essential for Transformation
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MYC Deregulation in Primary Human Cancers
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GENES (2017)
Strategies to Inhibit Myc and Their Clinical Applicability
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FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2017)
Pathogenesis and therapeutic targeting of aberrant MYC expression in haematological cancers
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KLF4 expression enhances the efficacy of chemotherapy drugs in ovarian cancer cells
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PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression
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MYC regulates the antitumor immune response through CD47 and PD-L1
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ONCOTARGET (2016)
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Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice
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MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
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MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition
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BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
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Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms
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A β-catenin/TCF-coordinated chromatin loop at MYC integrates 5′ and 3′ Wnt responsive enhancers
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Direct activation of RNA polymerase III transcription by c-Myc
N Gomez-Roman et al.
NATURE (2003)
Sustained loss of a neoplastic phenotype by brief inactivation of MYC
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The Max network gone mad
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