期刊
BIOTECHNOLOGY AND BIOENGINEERING
卷 118, 期 4, 页码 1545-1563出版社
WILEY
DOI: 10.1002/bit.27669
关键词
biochemicals; biofuels; biosensing; cell harvesting; cell sorting; microalgae; microfluidics
资金
- Alexander von Humboldt-Stiftung
- Marie Sklodowska-Curie Individual Fellowship award [101003361]
- Royal Academy Newton-Katip Celebi Transforming Systems Through Partnership Award [120N019]
- TUBITAK 2232 International Fellowship for Outstanding Researchers Award [118C391]
Microalgae have diversified applications in biofuels, biosensing, and other biotechnological products, but advanced technologies are needed to optimize the production processes.
Microalgae have expanded their roles as renewable and sustainable feedstocks for biofuel, smart nutrition, biopharmaceutical, cosmeceutical, biosensing, and space technologies. They accumulate valuable biochemical compounds from protein, carbohydrate, and lipid groups, including pigments and carotenoids. Microalgal biomass, which can be adopted for multivalorization under biorefinery settings, allows not only the production of various biofuels but also other value-added biotechnological products. However, state-of-the-art technologies are required to optimize yield, quality, and the economical aspects of both upstream and downstream processes. As such, the need to use microfluidic-based devices for both fundamental research and industrial applications of microalgae, arises due to their microscale sizes and dilute cultures. Microfluidics-based devices are superior to their competitors through their ability to perform multiple functions such as sorting and analyzing small amounts of samples (nanoliter to picoliter) with higher sensitivities. Here, we review emerging applications of microfluidic technologies on microalgal processes in cell sorting, cultivation, harvesting, and applications in biofuels, biosensing, drug delivery, and nutrition.
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