相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site
Guangcheng Wang et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)
Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking
Riham F. George et al.
BIOORGANIC CHEMISTRY (2020)
Design, synthesis and anticervical cancer activity of new benzofuran-pyrazol-hydrazono- thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents
Hebat-Allah S. Abbas et al.
BIOORGANIC CHEMISTRY (2019)
Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7
Eman F. Abdelhaleem et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Novel quinoline-3-carboxamides (Part 2): Design, optimization and synthesis of quinoline based scaffold as EGFR inhibitors with potent anticancer activity
Rasha M. Aly et al.
BIOORGANIC CHEMISTRY (2017)
Recently reported biological activities of pyrazole compounds
Jessica Venancia Faria et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Design, synthesis and biological evaluation of pyrazolyl-nitroimidazole derivatives as potential EGFR/HER-2 kinase inhibitors
Xiang-Xiang Tao et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Evaluation of apoptosis-associated protein (Bcl-2, Bax, cleaved caspase-3 and p53) expression in canine mammary tumors: An immunohistochemical and prognostic study
Izabella Dolka et al.
RESEARCH IN VETERINARY SCIENCE (2016)
Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery
Adile Ayati et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Copper-Catalyzed intramolecular Tandem Reaction of (2-Halogenphenyl)(3-phenyloxiran-2-yl)methanones: Synthesis of (Z)-Aurones
Yiyi Weng et al.
JOURNAL OF ORGANIC CHEMISTRY (2014)
Palladium-catalyzed direct intramolecular double α-C-H arylation of 1,5-diketone: a strategy for synthesis of Troger's base analogues
Jia Ju et al.
TETRAHEDRON LETTERS (2014)
Synthesis, molecular modeling and biological evaluation of cinnamic acid derivatives with pyrazole moieties as novel anticancer agents
Wei-Ming Zhang et al.
RSC ADVANCES (2014)
Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives containing benzodioxole as potential anticancer agents
Hai-Hong Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Synthesis of some dihydropyrimidine-based compounds bearing pyrazoline moiety and evaluation of their antiproliferative activity
Fadi M. Awadallah et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Design, synthesis and antiproliferative activity studies of novel 1,2,3-triazole-dithiocarbamate-urea hybrids
Ying-Chao Duan et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
A Novel Series of 3,4-Disubstituted Dihydropyrazoles: Synthesis and Evaluation for MAO Enzyme Inhibition
Maria Cristina Cardia et al.
JOURNAL OF HETEROCYCLIC CHEMISTRY (2013)
Design, synthesis and biological evaluation of pyrazolyl-thiazolinone derivatives as potential EGFR and HER-2 kinase inhibitors
Ke-Ming Qiu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Synthesis and biological validation of novel pyrazole derivatives with anticancer activity guided by 3D-QSAR analysis
Ines Vujasinovic et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Synthesis of pyrazole peptidomimetics and their inhibition against A549 lung cancer cells
Ying-Rui Liu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Molecular Docking: A Powerful Approach for Structure-Based Drug Discovery
Xuan-Yu Meng et al.
Current Computer-Aided Drug Design (2012)
Targeting the EGFR signaling pathway in cancer therapy
Parthasarathy Seshacharyulu et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2012)
Synthesis and preliminary evaluation activity studies of novel 4-(aryl/heteroaryl-2-ylmethyl)-6-phenyl-2-[3-(4-substituted-piperazine-1-yl)propyl]pyridazin-3(2H)-one derivatives as anticancer agents
M. S. R. Murty et al.
MEDICINAL CHEMISTRY RESEARCH (2012)
Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives as EGFR TK inhibitors and potential anticancer agents
Peng-Cheng Lv et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Hybrid Molecules Incorporating Natural Products: Applications in Cancer Therapy, Neurodegenerative Disorders and Beyond
M. Decker
CURRENT MEDICINAL CHEMISTRY (2011)
Synthesis and Biological Evaluation of New Fused Isoxazolo[4,5-d] Pyridazine Derivatives
Hassan M. Faidallah et al.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY (2011)
Synthesis of novel pyrazolic analogues of chalcones and their 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antitumor agents
Braulio Insuasty et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Novel C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents: Pyridazinylmethylphenyl glucoside congeners
Min Ju Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Design, synthesis, and structure-activity relationships of pyrazole derivatives as potential FabH inhibitors
Peng-Cheng Lv et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Novel chalcones and 1,3,5-triphenyl-2-pyrazoline derivatives as antibacterial agents
Ponnurengam Malliappan Sivakumar et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2010)
Synthesis, characterization and antihypertensive activity of pyridazinone derivatives
Anees A. Siddiqui et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Microwave-assisted synthesis and in-vitro anti-tumor activity of 1,3,4-triaryl-5-N-arylpyrazole-carboxamides
Hatem A. Abdel-Aziz et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Synthesis and biological evaluation of some novel 6-aryl-2-(p-sulfamylphenyl)-4,5-dihydropyridazin-3(2H)-ones as anti-cancer, antimicrobial, and anti-inflammatory agents
Shamim Ahmad et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2010)
Synthesis of new thiazole-2, -4, and -5-yl-(amino)methylphosphonates and phosphinates: unprecedented cleavage of thiazole-2 derivatives under acidic conditions
Tomasz Krzysztof Olszewski et al.
TETRAHEDRON (2010)
Design, synthesis and analgesic properties of novel conformationally-restricted N-acylhydrazones (NAH)
Arthur E. Kuemmerle et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Anti-epidermal growth factor receptor monoclonal antibodies in cancer treatment
Jaume Capdevila et al.
CANCER TREATMENT REVIEWS (2009)
Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities
Manuela Labbozzetta et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2009)
Design of New Drug Molecules to be Used in Reversing Multidrug Resistance in Cancer Cells
Y. C. Mayur et al.
CURRENT CANCER DRUG TARGETS (2009)
Convenient synthesis and antimicrobial evaluation of some novel 2-substituted-3-methylbenzofuran derivatives
Hatem A. Abdel-Aziz et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)
Design, synthesis, and biological evaluation of Mannich bases of heterocyclic chalcone analogs as cytotoxic agents
M. Vijaya Bhaskar Reddy et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Luminescent biological probes derived from ruthenium(II) estradiol polypyridine complexes
Kenneth Kam-Wing Lo et al.
INORGANIC CHEMISTRY (2008)
Homogeneous time-resolved fluorescence and its applications for kinase assays in drug discovery
Yong Jia et al.
ANALYTICAL BIOCHEMISTRY (2006)
In silico identification of novel EGFR inhibitors with antiproliferative activity against cancer cells
CN Cavasotto et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases
MF Braña et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Design, synthesis and anti-microbial activity of 1H-pyrazole carboxylates
R Sridhar et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Ab initio computation of electron affinities of substituted benzalacetophenones (chalcones): a new approach to substituent effects in organic electrochemistry
LD Hicks et al.
ELECTROCHIMICA ACTA (2004)
Phase-transfer catalyzed asymmetric epoxidation of chalcones using chiral crown ethers derived from D-glucose, D-galactose, and D-mannitol
T Bakó et al.
TETRAHEDRON-ASYMMETRY (2004)
Synthesis and evaluation of 5-arylated 2(5H)-furanones and 2-arylated pyridazin-3(2H)-ones as anti-cancer agents
E Lattmann et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2003)
The ErbB receptors and their role in cancer progression
T Holbro et al.
EXPERIMENTAL CELL RESEARCH (2003)
Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor
J Stamos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
H Ogiso et al.
CELL (2002)
The ErbB receptor tyrosine family as signal integrators
NE Hynes et al.
ENDOCRINE-RELATED CANCER (2001)
Role of conformational alteration in the epidermal growth factor receptor (EGFR) function
S Bishayee
BIOCHEMICAL PHARMACOLOGY (2000)
分享论文
