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A Novel Sialyltransferase Inhibitor AL10 Suppresses Invasion and Metastasis of Lung Cancer Cells by Inhibiting Integrin-Mediated Signaling
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Assessment of Chemoselective Neoglycosylation Methods Using Chlorambucil as a Model
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JOURNAL OF MEDICINAL CHEMISTRY (2010)
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
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ONCOGENE (2010)
Polymers for Drug Delivery Systems
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ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 1 (2010)
Glycosylation diseases: Quo vadis?
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
Overexpression of DPAGT1 Leads to Aberrant N-Glycosylation of E-Cadherin and Cellular Discohesion in Oral Cancer
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CANCER RESEARCH (2009)
Core fucosylation of E-cadherin enhances cell-cell adhesion in human colon carcinoma WiDr cells
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CANCER SCIENCE (2009)
Cotranslational and Posttranslational N-Glycosylation of Polypeptides by Distinct Mammalian OST Isoforms
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CELL (2009)
Increasing the Antigenicity of Synthetic Tumor-Associated Carbohydrate Antigens by Targeting Toll-Like Receptors
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CHEMBIOCHEM (2009)
Medicinal Chemistry of Paclitaxel and its Analogues
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CURRENT MEDICINAL CHEMISTRY (2009)
Breast cancer humoral immune response: involvement of Lewis y through the detection of circulating immune complexes and association with Mucin 1 (MUC1)
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JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2009)
Alteration of protein glycosylation in liver diseases
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JOURNAL OF HEPATOLOGY (2009)
Glucose Promoiety Enables Glucose Transporter Mediated Brain Uptake of Ketoprofen and Indomethacin Prodrugs in Rats
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JOURNAL OF MEDICINAL CHEMISTRY (2009)
From Synthesis to Biologics: Preclinical Data on a Chemistry Derived Anticancer Vaccine
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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
A Possible Role for Metallic Ions in the Carbohydrate Cluster Recognition Displayed by a Lewis Y Specific Antibody
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PLOS ONE (2009)
Glycoconjugates as vaccines for cancer immunotherapy: Clinical trials and future directions
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ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2008)
Expression analysis of carbohydrate antigens in ductal carcinoma in situ of the breast by lectin histochemistry
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BMC CANCER (2008)
Branched N-glycans regulate the biological functions of integrins and cadherins
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FEBS JOURNAL (2008)
Regulation of glycan structures in animal tissues - Transcript profiling of glycan-related genes
Alison V. Nairn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Glycan antagonists and inhibitors: A fount for drug discovery
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CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
Robust immune responses elicited by a fully synthetic three-component vaccine
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NATURE CHEMICAL BIOLOGY (2007)
Immunolocalisation of members of the polypeptide N-acetylgalactosaminyl transferase (ppGalNAc-T) family is consistent with biologically relevant altered cell surface glycosylation in breast cancer
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ACTA HISTOCHEMICA (2007)
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INTERNATIONAL JOURNAL OF CANCER (2006)
N-glycosylation affects the molecular organization and stability of E-cadherin junctions
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
UDP-N-acetyl-D-galactosamine:: Polypepticle N-acetylgalactosaminyltransferase-6 as a new immunohistochemical breast cancer marker
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JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2006)
ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity
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GLYCOBIOLOGY (2006)
Biomarkers in cancer staging, prognosis and treatment selection
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NATURE REVIEWS CANCER (2005)
Thomsen-Friedenreich (TF) antigen as a target for prostate cancer vaccine: clinical trial results with TF cluster (c)-KLH plus QS21 conjugate vaccine in patients with biochemically relapsed prostate cancer
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CANCER IMMUNOLOGY IMMUNOTHERAPY (2005)
Hypersialylation of β1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility
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CANCER RESEARCH (2005)
Synthesis and enzyme-specific activation of carbohydrate-geldanamycin conjugates with potent anticancer activity
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JOURNAL OF MEDICINAL CHEMISTRY (2005)
High expression of Lewis(y/b) antigens is associated with decreased survival in lymph node negative breast carcinomas
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BREAST CANCER RESEARCH (2005)
Towards a fully synthetic carbohydrate-based anticancer vaccine: Synthesis and immunological evaluation of a lipidated glycopeptide containing the tumor-associated Tn antigen
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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
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JOURNAL OF SURGICAL ONCOLOGY (2004)
β1,4-N-Acetylglucosaminyltransferase III down-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Ras/ERK signaling pathway in PC12 cells
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GLYCOBIOLOGY (2004)
The expression of core fucosylated E-cadherin in cancer cells and lung cancer patients: prognostic implications
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CELL RESEARCH (2004)
Carbohydrate structure and differential binding of prostate specific antigen to Maackia amurensis lectin between prostate cancer and benign prostate hypertrophy
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GLYCOBIOLOGY (2004)
The immunogenicity of the tumor-associated antigen Lewisy may be suppressed by a bifunctional cross-linker required for coupling to a carrier protein
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CHEMISTRY-A EUROPEAN JOURNAL (2004)
Mucins in cancer: Protection and control of the cell surface
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NATURE REVIEWS CANCER (2004)
N-acetylglucosaminyltransferase V expression levels regulate cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
MUC1 alters β-catenin-dependent tumor formation and promotes cellular invasion
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ONCOGENE (2003)
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer
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ONCOLOGY (2003)
Defective glycosylation in muscular dystrophy
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LANCET (2002)
The other side of TGF-β superfamily signal regulation:: thinking outside the cell
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TRENDS IN ENDOCRINOLOGY AND METABOLISM (2002)
Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl-Lewisa and sialyl-Lewisx antigens in colorectal adenocarcinoma
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HISTOPATHOLOGY (2002)
Protein glycosylation: nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds
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GLYCOBIOLOGY (2002)
Comparison of the lectin-binding pattern in different human melanoma cell lines
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MELANOMA RESEARCH (2001)
Intracellular functions of N-linked glycans
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SCIENCE (2001)
Toward optimized carbohydrate-based anticancer vaccines:: Epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewisy conjugates in mice
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
O-glycosylation of the mucin type
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BIOLOGICAL CHEMISTRY (2001)
Phase I trial of 6-hour infusion of glufosfamide, a new alkylating agent with potentially enhanced selectivity for tumors that overexpress transmembrane glucose transporters: A study of the European Organization for Research and Treatment of Cancer Early Clinical Studies Group
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JOURNAL OF CLINICAL ONCOLOGY (2000)