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JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
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MOLECULAR AND CELLULAR BIOLOGY (2011)
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JOURNAL OF CELL BIOLOGY (2010)
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ANALYTICAL BIOCHEMISTRY (2009)
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BMC GENOMICS (2009)
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CELL CYCLE (2009)
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CURRENT BIOLOGY (2009)
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DEVELOPMENTAL CELL (2009)
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JOURNAL OF CELL BIOLOGY (2009)
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JOURNAL OF DRUG TARGETING (2009)
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MOLECULAR AND CELLULAR BIOLOGY (2009)
Polo-Like Kinase 1 Depletion Induces DNA Damage in Early S Prior to Caspase Activation
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MOLECULAR AND CELLULAR BIOLOGY (2009)
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Sven Kappel et al.
NUCLEIC ACIDS RESEARCH (2006)
Epigenetic inactivation implies a tumor suppressor function in hematologic malignancies for Polo-like kinase 2 but not Polo-like kinase 3
Paul Smith et al.
CELL CYCLE (2006)
Down-regulation of polo-like kinase 1 elevates drug sensitivity of breast cancer cells in vitro and in vivo
Birgit Spaenkuch et al.
CANCER RESEARCH (2006)
Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis
N Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage
EM Bahassi et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2006)
Opinion - Targeting polo-like kinase 1 for cancer therapy
K Strebhardt et al.
NATURE REVIEWS CANCER (2006)
Transcriptional silencing of Polo-like kinase 2 (SNK/PLK2) is a frequent event in B-cell malignancies
N Syed et al.
BLOOD (2006)
Small molecules keep mitotic kinases in check
Klaus Strebhardt
ACS CHEMICAL BIOLOGY (2006)
SAK/PLK4 is required for centriole duplication and flagella development
M Bettencourt-Dias et al.
CURRENT BIOLOGY (2005)
The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress
F Staib et al.
CANCER RESEARCH (2005)
The Polo kinase Plk4 functions in centriole duplication
R Habedanck et al.
NATURE CELL BIOLOGY (2005)
Identification of novel p53 target genes in ionizing radiation response
KY Jen et al.
CANCER RESEARCH (2005)
Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis
MA Ko et al.
NATURE GENETICS (2005)
Function of polo-like kinase 3 in NF-κB-mediated proapoptotic response
ZK Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Conditional inhibition of cancer cell proliferation by tetracycline-responsive, H1 promoter-driven silencing of PLK1
Y Matthess et al.
ONCOGENE (2005)
Polo-like kinase isoforms in breast cancer:: expression patterns and prognostic implications
W Weichert et al.
VIRCHOWS ARCHIV (2005)
SAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencing
J Li et al.
NEOPLASIA (2005)
Interaction of chromatin-associated Plk1 and Mcm7
L Tsvetkov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Differential regulation of polo-like kinase 1, 2, 3, and 4 gene expression in mammalian cells and tissues
JA Winkles et al.
ONCOGENE (2005)
Polo-like kinases and oncogenesis
F Eckerdt et al.
ONCOGENE (2005)
Sak/Plk4 and mitotic fidelity
CJ Swallow et al.
ONCOGENE (2005)
RNA interference-based gene silencing in mice: The development of a novel therapeutical strategy
B Spankuch et al.
CURRENT PHARMACEUTICAL DESIGN (2005)
Microtubules as a target for anticancer drugs
MA Jordan et al.
NATURE REVIEWS CANCER (2004)
H2AX: the histone guardian of the genome
O Fernandez-Capetillo et al.
DNA REPAIR (2004)
Polo-like kinase-2 is required for centriole duplication in mammalian cells
S Warnke et al.
CURRENT BIOLOGY (2004)
MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals
D Sheikh-Hamad et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
Micrornas: Small RNAs with a big role in gene regulation
L He et al.
NATURE REVIEWS GENETICS (2004)
Cancer inhibition in nude mice after systemic application of U6 promoter-driven short hairpin RNAs against PLK1
B Spänkuch et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2004)
Polo-like kinases and the orchestration of cell division
FA Barr et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Tumour cell delivery of antisense oligonucleotides by human serum albumin nanoparticles
H Wartlick et al.
JOURNAL OF CONTROLLED RELEASE (2004)
p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis
PS Kho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Highly specific HER2-mediated cellular uptake of antibody-modified nanoparticles in tumour cells
H Wartlick et al.
JOURNAL OF DRUG TARGETING (2004)
MEK1-induced Golgi dynamics during cell cycle progression is partly mediated by Polo-like kinase-3
SQ Xie et al.
ONCOGENE (2004)
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain
AEH Elia et al.
CELL (2003)
Role of Plk2 (Snk) in mouse development and cell proliferation
S Ma et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (Taxol)-exposed cells
TF Burns et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells
XQ Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells
B Spänkuch-Schmitt et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2002)
The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization
GC Leung et al.
NATURE STRUCTURAL BIOLOGY (2002)
Mammalian Polo-like kinase 3 (PIU) is a multifunctional protein involved in stress response pathways
EM Bahassi et al.
ONCOGENE (2002)
Dual mode of degradation of Cdc25 A phosphatase
M Donzelli et al.
EMBO JOURNAL (2002)
Expression of polo-like kinase (PLK1) in thin melanomas: a novel marker of metastatic disease
L Kneisel et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2002)
Downregulation of human polo-like kinase activity by antisense oligonucleotides induces growth inhibition in cancer cells
B Spänkuch-Schmitt et al.
ONCOGENE (2002)
Cell cycle arrest and apoptosis induced by human polo-like kinase 3 is mediated through perturbation of microtubule integrity
Q Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Functional studies on the role of the C-terminal domain of mammalian polo-like kinase
YJ Jang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Identification of high risk breast-cancer patients by gene expression profiling
A Ahr et al.
LANCET (2002)
Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells
T Ohta et al.
JOURNAL OF CELL BIOLOGY (2002)
Intron/exon organization and polymorphisms of the PLK3/PRK gene in human lung carcinoma cell lines
J Wiest et al.
GENES CHROMOSOMES & CANCER (2001)
Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway
SQ Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Comparative expression of the mitotic regulators SAK and PLK in colorectal cancer
JC Macmillan et al.
ANNALS OF SURGICAL ONCOLOGY (2001)
Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3
SQ Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
AP-1 in cell proliferation and survival
E Shaulian et al.
ONCOGENE (2001)
TOR, a central controller of cell growth
T Schmelzle et al.
CELL (2000)
Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages
U Holtrich et al.
ONCOGENE (2000)
Prognostic value of pololike kinase expression in melanomas
K Strebhardt et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)
Essential function of the polo box of Cdc5 in subcellular localization and induction of cytokinetic structures
S Song et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Polo-like kinase: a novel marker of proliferation: Correlation with estrogen-receptor expression in human breast cancer
G Wolf et al.
PATHOLOGY RESEARCH AND PRACTICE (2000)
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