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JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The Endoplasmic Reticulum Grp170 Acts as a Nucleotide Exchange Factor of Hsp70 via a Mechanism Similar to That of the Cytosolic Hsp110
Claes Andreasson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin
Bradley R. Pearse et al.
JOURNAL OF CELL BIOLOGY (2010)
Modularity of the Hrd1 ERAD complex underlies its diverse client range
Kazue Kanehara et al.
JOURNAL OF CELL BIOLOGY (2010)
Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LS substrates
Riccardo Bernasconi et al.
JOURNAL OF CELL BIOLOGY (2010)
Organization of the Sec61 Translocon, Studied by High Resolution Native Electrophoresis
Kurt Dejgaard et al.
JOURNAL OF PROTEOME RESEARCH (2010)
The Endoplasmic Reticulum-associated Degradation of the Epithelial Sodium Channel Requires a Unique Complement of Molecular Chaperones
Teresa M. Buck et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Structural Basis for Oligosaccharide Recognition of Misfolded Glycoproteins by OS-9 in ER-Associated Degradation
Tadashi Satoh et al.
MOLECULAR CELL (2010)
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
Shinichiro Nakada et al.
NATURE (2010)
Molecular characterization of the endoplasmic reticulum: Insights from proteomic studies
Xuequn Chen et al.
PROTEOMICS (2010)
UDP-GlC:glycoprotein glucosyltransferase-glucosidase II, the ying-yang of the ER quality control
Cecilia D'Alessio et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
Protein Disulfide Isomerase: A Critical Evaluation of Its Function in Disulfide Bond Formation
Feras Hatahet et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Functional Roles of Ubiquitin-Like Domain (ULD) and Ubiquitin-Binding Domain (UBD) Containing Proteins
Caroline Grabbe et al.
CHEMICAL REVIEWS (2009)
Chemical approaches toward understanding glycan-mediated protein quality control
Yoichi Takeda et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2009)
Roles of Protein-disulfide Isomerase-mediated Disulfide Bond Formation of Yeast Mnl1p in Endoplasmic Reticulum-associated Degradation
Machiko Sakoh-Nakatogawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Nucleotide Binding by Lhs1p Is Essential for Its Nucleotide Exchange Activity and for Function in Vivo
Jeanine de Keyzer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Human OS-9, a Lectin Required for Glycoprotein Endoplasmic Reticulum-associated Degradation, Recognizes Mannose-trimmed N-Glycans
Nobuko Hosokawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER
Helen R. Stagg et al.
JOURNAL OF CELL BIOLOGY (2009)
Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum
Simone Clerc et al.
JOURNAL OF CELL BIOLOGY (2009)
A Ubc7p-binding domain in Cue1p activates ER-associated protein degradation
Zlatka Kostova et al.
JOURNAL OF CELL SCIENCE (2009)
The E3 Ubiquitin Ligase TEB4 Mediates Degradation of Type 2 Iodothyronine Deiodinase
Ann Marie Zavacki et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Intrinsic Conformational Determinants Signal Protein Misfolding to the Hrd1/Htm1 Endoplasmic Reticulum-associated Degradation System
Wei Xie et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
EDEM1 Recognition and Delivery of Misfolded Proteins to the SEL1L-Containing ERAD Complex
James H. Cormier et al.
MOLECULAR CELL (2009)
The Otubain YOD1 Is a Deubiquitinating Enzyme that Associates with p97 to Facilitate Protein Dislocation from the ER
Robert Ernst et al.
MOLECULAR CELL (2009)
Usa1 Functions as a Scaffold of the HRD-Ubiquitin Ligase
Sabine C. Horn et al.
MOLECULAR CELL (2009)
The human PDI family: Versatility packed into a single fold
Christian Apperizeller-Herzog et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Dissecting the ER-Associated degradation of a misfolded polytopic membrane protein
Kunio Nakatsukasa et al.
CELL (2008)
The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p
Veit Goder et al.
FEBS LETTERS (2008)
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
Hideki Nishitoh et al.
GENES & DEVELOPMENT (2008)
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP
Nobuko Hosokawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum - Inhibiting secretion of misfolded protein conformers and enhancing their disposal
Riccardo Bernasconi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo
Omar A. Bazirgan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRΔF508
Daisuke Morito et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C
Mei Dong et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Derlin-1 facilitates the retro-translocation of cholera toxin
Kaleena M. Bernardi et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Malectin:: A novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation
Thomas Schallus et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man(5-6)GlcNAc(2) in glycoprotein ER-associated degradation
Edward Avezov et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Defining the Glycan Destruction Signal for Endoplasmic Reticulum-Associated Degradation
Erin M. Quan et al.
MOLECULAR CELL (2008)
OS-9 and GRP94 deliver mutant α1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD
John C. Christianson et al.
NATURE CELL BIOLOGY (2008)
SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins
Britta Mueller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER
Ryo Ushioda et al.
SCIENCE (2008)
O-mannosylation is required for degradation of the endoplasmic reticulum-associated degradation substrate Gas1*p via the ubiquitin/proteasome pathway in Saccharomyces cerevisiae
Hiroto Hirayama et al.
JOURNAL OF BIOCHEMISTRY (2008)
Characterization of an ERAD pathway for nonglyclosylated BiP substrates, which require Herp
Yuki Okuda-Shimizu et al.
MOLECULAR CELL (2007)
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6α and XBP1
Keisuke Yamamoto et al.
DEVELOPMENTAL CELL (2007)
The role of p58IPK in protecting the stressed endoplasmic reticulum
D. Thomas Rutkowski et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78
Joon No Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants
Fei Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Man2C1, an α-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol
Tadashi Suzuki et al.
BIOCHEMICAL JOURNAL (2006)
EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation
Silvia Olivari et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER
Britta Mueller et al.
JOURNAL OF CELL BIOLOGY (2006)
Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis
Brian K. Sato et al.
YEAST (2006)
Cloning and expression of mouse cytosolic α-mannosidase (Man2cl)
Egidia Costanzi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)
Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload
Seiichi Oyadomari et al.
CELL (2006)
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator
J. Michael Younger et al.
CELL (2006)
A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery
Robert Gauss et al.
NATURE CELL BIOLOGY (2006)
Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins
Pedro Carvalho et al.
CELL (2006)
A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation
Vladimir Denic et al.
CELL (2006)
The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor
Guangtao Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition
CM Cruciat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment
Robert Gauss et al.
EMBO JOURNAL (2006)
EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming
K Hirao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Yeast GTB1 encodes a subunit of glucosidase II required for glycoprotein processing in the endoplasmic reticulum
BM Wilkinson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)
SG Kreft et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways
T Ravid et al.
EMBO JOURNAL (2006)
Structures and mechanisms of glycosyltransferases
C Breton et al.
GLYCOBIOLOGY (2006)
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
Y Oda et al.
JOURNAL OF CELL BIOLOGY (2006)
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane
BN Lilley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation
C Schuberth et al.
NATURE CELL BIOLOGY (2005)
Ubx2 links the Cdc48 complex to ER-associated protein degradation
O Neuber et al.
NATURE CELL BIOLOGY (2005)
Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen
A Bhamidipati et al.
MOLECULAR CELL (2005)
Yos9p detects and targets misfolded glycoproteins for ER-associated degradation
W Kim et al.
MOLECULAR CELL (2005)
Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase
BL Song et al.
MOLECULAR CELL (2005)
Yos9 protein is essential for degradation of misfolded glycoproteins and may function as lectin in ERAD
R Szathmary et al.
MOLECULAR CELL (2005)
More than one glycan is needed for ER glucosidase II to allow entry of glycoproteins into the calnexin/calreticulin cycle
P Deprez et al.
MOLECULAR CELL (2005)
TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum
G Hassink et al.
BIOCHEMICAL JOURNAL (2005)
Mechanism of class 1 (Glycosylhydrolase family 47) α-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control
K Karaveg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins
SW Mast et al.
GLYCOBIOLOGY (2005)
Importance of carbohydrate positioning in the recognition of mutated CPY for ER-associated degradation
Z Kostova et al.
JOURNAL OF CELL SCIENCE (2005)
Essential role of synoviolin in embryogenesis
N Yagishita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation
S Olivari et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
ERdj3, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates
Y Shen et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins
R Hitt et al.
FEMS YEAST RESEARCH (2004)
Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control
S Vashist et al.
JOURNAL OF CELL BIOLOGY (2004)
Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum
M Kikkert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Demonstration of mammalian protein O-mannosyltransferase activity:: Coexpression of POMT1 and POMT2 required for enzymatic activity
H Manya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
DER7, encoding α-glucosidase I is essential for degradation of malfolded glycoproteins of the endoplasmic reticulum
R Hitt et al.
FEMS YEAST RESEARCH (2004)
A foldable CFTRΔF508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase
JM Younger et al.
JOURNAL OF CELL BIOLOGY (2004)
P-domain and lectin site are involved in the chaperone function of Saccharomyces cerevisiae calnexin homologue
XH Xu et al.
FEBS LETTERS (2004)
Roles of O-mannosylation of aberrant proteins in reduction of the load for endoplasmic reticulum chaperones in yeast
K Nakatsukasa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The contributions of protein disulfide isomerase and its homologues to oxidative protein folding in the yeast endoplasmic reticulum
RY Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A genome-wide screen identifies Yos9p as essential for ER-associated degradation of glycoproteins
BA Buschhorn et al.
FEBS LETTERS (2004)
A membrane protein required for dislocation of misfolded proteins from the ER
BN Lilley et al.
NATURE (2004)
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
YH Ye et al.
NATURE (2004)
Enhancement of endoplasmic reticulum (ER) degradation of misfolded null Hong Kong α1-antitrypsin by human ER mannosidase I
N Hosokawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ngly1, a mouse gene encoding a deglycosylating enzyme implicated in proteasomal degradation:: expression, genomic organization, and chromosomal mapping
T Suzuki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle
M Molinari et al.
SCIENCE (2003)
EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin
Y Oda et al.
SCIENCE (2003)
Processing of N-linked carbohydrate chains in a patient with glucosidase I deficiency (CDG type IIb)
C Völker et al.
GLYCOBIOLOGY (2002)
Endo-β-N-acetylglucosaminidase, an enzyme involved in processing of free oligosaccharides in the cytosol
T Suzuki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress
Y Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Different effects of calnexin deletion in Saccharomyces cerevisiae on the secretion of two glycosylated amyloidogenic lysozymes
YT Song et al.
FEBS LETTERS (2002)
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48
E Jarosch et al.
NATURE CELL BIOLOGY (2002)
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
YH Ye et al.
NATURE (2001)
The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum
SY Fang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Effects of calnexin deletion in Saccharomyces cerevisiae on the secretion of glycosylated lysozymes
YT Song et al.
JOURNAL OF BIOCHEMISTRY (2001)
Rad23 provides a link between the Png1 deglycosylating enzyme and the 26 S proteasome in yeast
T Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A novel quality control compartment derived from the endoplasmic reticulum
S Kamhi-Nesher et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation
S Nishikawa et al.
JOURNAL OF CELL BIOLOGY (2001)
Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits - Involvement of ER-associated ubiquitin-conjugating enzymes (E2s)
S Tiwari et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Functional differences in yeast protein disulfide isomerases
P Norgaard et al.
JOURNAL OF CELL BIOLOGY (2001)
Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation
NW Bays et al.
NATURE CELL BIOLOGY (2001)
Structural basis for catalysis and inhibition of N-glycan processing class I α1,2-mannosidases
F Vallée et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum
JR Tyson et al.
EMBO JOURNAL (2000)
Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress
K Kokame et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Endoplasmic reticulum degradation requires lumen to cytosol signaling: Transmembrane control of Hrd1p by Hrd3p
RG Gardner et al.
JOURNAL OF CELL BIOLOGY (2000)
The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo
MF Pelletier et al.
GLYCOBIOLOGY (2000)
PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase
T Suzuki et al.
JOURNAL OF CELL BIOLOGY (2000)
Mammalian Sec61 is associated with Sec62 and Sec63
HA Meyer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cloning and characterization of mammalian UDP-glucose glycoprotein: glucosyltransferase and the development of a specific substrate for this enzyme
DC Tessier et al.
GLYCOBIOLOGY (2000)