Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds

The concise preparation of 4,4,4-trifluorobut-2-yn-1-ones by the oxidation of the readily accessible corresponding propargylic alcohols as well as their utilization as Michael acceptors for the construction of aromatic and heteroaromatic compounds are reported.

Automated summary

The study presents a concise method for preparing 4,4,4-trifluorobut-2-yn-1-ones by oxidizing readily accessible propargylic alcohols, and demonstrates their use as Michael acceptors for constructing aromatic and heteroaromatic compounds.