相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Metformin reduces prion infection in neuronal cells by enhancing autophagy
Dalia H. Abdelaziz et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Chemical analysis of saffron by HPLC based crocetin estimation
Chilakala Nagarjuna Reddy et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2020)
Sex-driven modifiers of Alzheimer risk A multimodality brain imaging study
Aneela Rahman et al.
NEUROLOGY (2020)
Diverse proteins aggregate in mild cognitive impairment and Alzheimer's disease brain
Devin Kepchia et al.
ALZHEIMERS RESEARCH & THERAPY (2020)
Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway
Abubakar Wani et al.
AUTOPHAGY (2019)
The Crocus sativus Compounds trans-Crocin 4 and trans-Crocetin Modulate the Amyloidogenic Pathway and Tau Misprocessing in Alzheimer Disease Neuronal Cell Culture Models
Ioanna Chalatsa et al.
FRONTIERS IN NEUROSCIENCE (2019)
Sex-specific relationship of cardiometabolic syndrome with lower cortical thickness
Si Eun Kim et al.
NEUROLOGY (2019)
Autophagy impairment by caspase-1-dependent inflammation mediates memory loss in response to -Amyloid peptide accumulation
Lourdes Alvarez-Arellano et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2018)
Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease
Maria Manczak et al.
HUMAN MOLECULAR GENETICS (2018)
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death
Stefano Thellung et al.
CELL DEATH & DISEASE (2018)
Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications
Md. Sahab Uddin et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
Sex Differences in Autophagy Contribute to Female Vulnerability in Alzheimer's Disease
Erin E. Congdon
FRONTIERS IN NEUROSCIENCE (2018)
Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice
Jin Zhang et al.
IMMUNITY & AGEING (2018)
Co-Localization of Glia Maturation Factor with NLRP3 Inflammasome and Autophagosome Markers in Human Alzheimer's Disease Brain
Mohammad Ejaz Ahmed et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients
Roberto Tiribuzi et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2017)
Crocetin Potentiates Neurite Growth in Hippocampal Neurons and Facilitates Functional Recovery in Rats with Spinal Cord Injury
Xiqian Wang et al.
NEUROSCIENCE BULLETIN (2017)
The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms
Tibor Kovacs et al.
SCIENTIFIC REPORTS (2017)
Crocus sativus Extract Tightens the Blood-Brain Barrier, Reduces Amyloid β Load and Related Toxicity in 5XFAD Mice
Yazan S. Batarseh et al.
ACS CHEMICAL NEUROSCIENCE (2017)
Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
Jessica J. Howell et al.
CELL METABOLISM (2017)
Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro
Carolin Walter et al.
NEUROPHARMACOLOGY (2016)
Cilostazol Modulates Autophagic Degradation of β-Amyloid Peptide via SIRT1-Coupled LKB1/AMPKα Signaling in Neuronal Cells
So Youn Park et al.
PLOS ONE (2016)
Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins
Stjepko Cermak et al.
PLOS ONE (2016)
The Role of Posttraumatic Hypothermia in Preventing Dendrite Degeneration and Spine Loss after Severe Traumatic Brain Injury
Chuan-fang Wang et al.
SCIENTIFIC REPORTS (2016)
Clearance systems in the brain-implications for Alzheimer disease
Jenna M. Tarasoff-Conway et al.
NATURE REVIEWS NEUROLOGY (2015)
Intestinal formation of trans-crocetin from saffron extract (Crocus sativus L.) and in vitro permeation through intestinal and blood brain barrier
M. Lautenschlager et al.
PHYTOMEDICINE (2015)
Dual roles for autophagy: Degradation and secretion of Alzheimer's disease Aβ peptide
Per Nilsson et al.
BIOESSAYS (2014)
Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy
Teng Jiang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Improving the prediction of drug disposition in the brain
Kiril Lanevskij et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2013)
Aβ Secretion and Plaque Formation Depend on Autophagy
Per Nilsson et al.
CELL REPORTS (2013)
Control of autophagy as a therapy for neurodegenerative disease
Harry Harris et al.
NATURE REVIEWS NEUROLOGY (2012)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status
X. Stephenne et al.
DIABETOLOGIA (2011)
Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-beta peptide degradation
Valerie Vingtdeux et al.
FASEB JOURNAL (2011)
Crocetin reduces the oxidative stress induced reactive oxygen species in the stroke-prone spontaneously hypertensive rats (SHRSPs) brain
Fumihiko Yoshino et al.
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
SAFFRON EXTRACT AND TRANS-CROCETIN INHIBIT GLUTAMATERGIC SYNAPTIC TRANSMISSION IN RAT CORTICAL BRAIN SLICES
F. Berger et al.
NEUROSCIENCE (2011)
Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson's Disease
Yuncheng Wu et al.
NEUROSIGNALS (2011)
Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits
Smita Majumder et al.
PLOS ONE (2011)
Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau EFFECTS ON COGNITIVE IMPAIRMENTS
Antonella Caccamo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Autophagy Dysfunction in Alzheimer's Disease
Liang Li et al.
NEURODEGENERATIVE DISEASES (2010)
MECHANISMS OF DISEASE Alzheimer's Disease
Henry W. Querfurth et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model
Andrey S. Tsvetkov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans
Della C. David et al.
PLOS BIOLOGY (2010)
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
Anne Simonsen et al.
AUTOPHAGY (2008)
Retinoic Acid Attenuates β-Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model
Yun Ding et al.
JOURNAL OF NEUROSCIENCE (2008)
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
Barry Boland et al.
JOURNAL OF NEUROSCIENCE (2008)
Autophagy, amyloidogenesis and Alzheimer disease
Ralph A. Nixon
JOURNAL OF CELL SCIENCE (2007)
The number of pregnancies is a risk factor for Alzheimer's disease
M. Colucci et al.
EUROPEAN JOURNAL OF NEUROLOGY (2006)
Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations:: Potential factors in amyloid plaque formation
Holly Oakley et al.
JOURNAL OF NEUROSCIENCE (2006)
AMP-activated protein kinase signaling in metabolic regulation
Yun Chau Long et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Macroautophagy -: a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
WH Yu et al.
JOURNAL OF CELL BIOLOGY (2005)
Pathways towards and away from Alzheimer's disease
MP Mattson
NATURE (2004)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)