期刊
ANNALS OF THORACIC SURGERY
卷 112, 期 5, 页码 1600-1608出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.athoracsur.2020.11.022
关键词
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资金
- Perioperative Program Charitable Foundation, Montreal, Quebec, Canada
- Fonds de Recherche du Quebec - Sante
- McGill University Health Centre Research Institute
- Mitacs (Accelerate Fellowship Program)
For patients undergoing lung cancer resection within an enhanced recovery pathway, a multimodal prehabilitation program initiated 4 weeks before operation is as effective in recovering functional capacity as multimodal rehabilitation.
Background. The study was conducted to determine whether a multimodal prehabilitation program enhances postoperative functional recovery compared with multimodal rehabilitation. Methods. Patients scheduled for non-small cell lung cancer resection were randomized to 2 groups receiving home-based moderate-intensity exercise, nutritional counseling with whey protein supplementation, and anxiety-reducing strategies for 4 weeks before the operation (PREHAB, n = 52) or 8 weeks after (REHAB, n = 43). Functional capacity (FC) was measured by the 6-minute walk test (6MWT) at baseline, immediately before the operation, and 4 and 8 weeks after operation. All patients were treated according to enhanced recovery pathway guidelines. Results. There was no difference in FC at any point during the perioperative period between the 2 multimodal programs. By 8 weeks after operation, both groups returned to baseline FC, and a similar proportion of patients (>75%) in both groups had recovered to their baseline. Conclusions. In patients undergoing surgical resection for lung cancer within the context of an enhanced recovery pathway, multimodal prehabilitation initiated 4 weeks before operation is as effective in recovering FC as multimodal rehabilitation. (C) 2021 by The Society of Thoracic Surgeons
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