期刊
AMERICAN JOURNAL OF TRANSPLANTATION
卷 21, 期 5, 页码 1948-1952出版社
WILEY
DOI: 10.1111/ajt.16399
关键词
clinical research; practice; genetics; kidney transplantation; nephrology; recurrent disease
CG is a rare disease characterized by collagen type 3 fibrils deposition in glomeruli, leading to proteinuria, hematuria, and renal dysfunction. Definitive diagnosis is made via electron microscopy, showing characteristic curved, comma-like, banded fibers. This is the first case report of CG in a kidney transplant recipient with unknown kidney disease etiology.
Collagenofibrotic glomerulopathy (CG) is a rare disease characterized by the deposition of collagen type 3 fibrils in the glomeruli. Patients may have proteinuria, hematuria, and/or renal dysfunction. CG is considered a progressive disease with variable rates of progression. The definitive diagnosis is made by electron microscopy with the presence of characteristic subendothelial and mesangial curved, comma-like, banded collagen type 3 fibers of 40-65 nm periodicity. We are reporting the first case of CG in a kidney transplant recipient with kidney disease of unknown cause.
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