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CELL METABOLISM (2008)
Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity
Leonie K. Heilbronn et al.
CURRENT PHARMACEUTICAL DESIGN (2008)
The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members
Thalia A. Farazi et al.
DEVELOPMENT (2008)
Intake of fruit, vegetables, and fruit juices and risk of diabetes in women
Lydia A. Bazzano et al.
DIABETES CARE (2008)
Effects of different cooking methods on nutritional and physicochemical characteristics of selected vegetables
Cristiana Miglio et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
Vered Elgazar-Carmon et al.
JOURNAL OF LIPID RESEARCH (2008)
Sulforaphane Induces Cell-Cycle Arrest and Apoptosis in Cultured Human Lung Adenocarcinoma LTEP-A2 Cells and Retards Growth of LTEP-A2 Xenografts in Vivo
Hao Liang et al.
JOURNAL OF NATURAL PRODUCTS (2008)
Seasonal variation in glucosinolate content in Brassica oleracea crops grown in northwestern Spain
Maria Elena Cartea et al.
PHYTOCHEMISTRY (2008)
Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration
M. E. Rausch et al.
INTERNATIONAL JOURNAL OF OBESITY (2008)
De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc
L. G. Wang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2008)
Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl lsothiocyanate and phenyl lsothiocyanate
P. Thejass et al.
INTEGRATIVE CANCER THERAPIES (2007)
Adipocyte death, adipose tissue remodeling, and obesity complications
Katherine J. Strissel et al.
DIABETES (2007)
Increased consumption of fruit and vegetables is related to a reduced risk of coronary heart disease: meta-analysis of cohort studies
F. J. He et al.
JOURNAL OF HUMAN HYPERTENSION (2007)
Phenethyl isothiocyanate inhibits angiogenesis in vitro and ex vivo
Dong Xiao et al.
CANCER RESEARCH (2007)
T-cell accumulation and regulated on activation, normal T cell expressed and secreted Upregulation in adipose tissue in obesity
Huaizhu Wu et al.
CIRCULATION (2007)
Effect of storage, processing and cooking on glucosinolate content of Brassica vegetables
Lijiang Song et al.
FOOD AND CHEMICAL TOXICOLOGY (2007)
Effect of cooking brassica vegetables on the subsequent hydrolysis and metabolic fate of glucosinolates
Vanessa Rungapamestry et al.
PROCEEDINGS OF THE NUTRITION SOCIETY (2007)
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis
Jane V. Higdon et al.
PHARMACOLOGICAL RESEARCH (2007)
Single-dose and multiple-dose administration of indole-3-carbinol to women:: Pharmacokinetics based on 3,3′-diindolylmethane
Gregory A. Reed et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2006)
Benzyl isothiocyanate-induced DNA damage causes G2/M cell cycle arrest and apoptosis in human pancreatic cancer cells
Ruifen Zhang et al.
JOURNAL OF NUTRITION (2006)
Advanced glycation end products - Sparking the development of diabetic vascular injury
Alison Goldin et al.
CIRCULATION (2006)
Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2
Changjiang Xu et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Separation of human adipocytes by size:: hypertrophic fat cells display distinct gene expression
Margareta Jernas et al.
FASEB JOURNAL (2006)
A pericellular collagenase directs the 3-dimensional development of white adipose tissue
Tae-Hwa Chun et al.
CELL (2006)
Potent activation of mitochondria-mediated apoptosis and arrest in S and M phases of cancer cells by a broccoli sprout extract
L Tang et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells
MC Myzak et al.
CARCINOGENESIS (2006)
ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells
CJ Xu et al.
CARCINOGENESIS (2006)
Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention
E Bertl et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells
CT Brew et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Effects of Indole-3-Carbinol and phenethyl isothiocyanate on colon carcinogenesis induced by azoxymethane in rats
AYA Plate et al.
CARCINOGENESIS (2006)
Fruit and vegetable consumption and risk of epithelial ovarian cancer:: The European prospective investigation into cancer and nutrition
M Schulz et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2005)
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
S Cinti et al.
JOURNAL OF LIPID RESEARCH (2005)
A phase I study of indole-3-carbinol in women: Tolerability and effects
GA Reed et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2005)
Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: A review
S Singhal et al.
CLINICAL CANCER RESEARCH (2005)
Proposed criteria for assessing the efficacy of cancer reduction by plant foods enriched in carotenoids, glucosinolates, polyphenols and selenocompounds
JW Finley
ANNALS OF BOTANY (2005)
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
MF Fraga et al.
NATURE GENETICS (2005)
Consumption of vegetables and fruits and risk of breast cancer
CH van Gils et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
Molecular targets and anticancer potential of indole-3-carbinol and its derivatives
BB Aggarwal et al.
CELL CYCLE (2005)
In vitro digestion of sinigrin and glucotropaeolin by single strains of Bifidobacterium and identification of the digestive products
DL Cheng et al.
FOOD AND CHEMICAL TOXICOLOGY (2004)
Dietary isothiocyanates inhibit the growth of human bladder carcinoma cells
L Tang et al.
JOURNAL OF NUTRITION (2004)
Allyl-isothiocyanate causes mitotic block, loss of cell adhesion and disrupted cytoskeletal structure in HT29 cells
TK Smith et al.
CARCINOGENESIS (2004)
Pharmacokinetics and tissue disposition of indole-3-carbinol and its acid condensation products after oral administration to mice
MJ Anderton et al.
CLINICAL CANCER RESEARCH (2004)
Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo
AV Singh et al.
CARCINOGENESIS (2004)
Dietary isothiocyanates inhibit Caco-2 cell proliferation and induce G2/M phase cell cycle arrest, DNA damage, and G2/M checkpoint activation
JM Visanji et al.
JOURNAL OF NUTRITION (2004)
A critical review of the bioavailability of glucosinolates and related compounds
B Holst et al.
NATURAL PRODUCT REPORTS (2004)
Physiological modeling of formulated and crystalline 3,3′-diindolylmethane pharmacokinetics following oral administration in mice
MJ Anderton et al.
DRUG METABOLISM AND DISPOSITION (2004)
Benzyl isothiocyanate modifies expression of the G(2)/M arrest-related genes
N Miyoshi et al.
BIOFACTORS (2004)
Glycation, inflammation, and RAGE - A scaffold for the macrovascular complications of diabetes and beyond
SF Yan et al.
CIRCULATION RESEARCH (2003)
Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC)
YS Keum et al.
PHARMACEUTICAL RESEARCH (2003)
The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells
R Hu et al.
CARCINOGENESIS (2003)
Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo
N Petri et al.
DRUG METABOLISM AND DISPOSITION (2003)
Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis
D Xiao et al.
CARCINOGENESIS (2003)
Cell-cycle dysregulation and anticancer therapy
ZA Stewart et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2003)
Cyclin D3 and p53 mediate sulforaphane-induced cell cycle delay and apoptosis in non-transformed human T lymphocytes
C Fimognari et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2002)
Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model
C Krul et al.
CARCINOGENESIS (2002)
Isothiocyanates as cancer chemopreventive agents: Their biological activities and metabolism in rodents and humans
CC Conaway et al.
CURRENT DRUG METABOLISM (2002)
High cellular accumulation of sulphoraphane, a dietary anticarcinogen, is followed by rapid transporter-mediated export as a glutathione conjugate
YS Zhang et al.
BIOCHEMICAL JOURNAL (2002)
Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane
C Fimognari et al.
CARCINOGENESIS (2002)
Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans
LX Ye et al.
CLINICA CHIMICA ACTA (2002)
A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway
Y Morimitsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and influences Trichoplusia ni herbivory
V Lambrix et al.
PLANT CELL (2001)
Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium
DZ Chen et al.
JOURNAL OF NUTRITION (2001)
The synergistic upregulation of phase II detoxification enzymes by glucosinolate breakdown products in cruciferous vegetables
CW Nho et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2001)
Genetic control of natural variation in Arabidopsis glucosinolate accumulation
DJ Kliebenstein et al.
PLANT PHYSIOLOGY (2001)
Indole3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells
SR Chinni et al.
ONCOGENE (2001)
Formation of allyl isothiocyanate from sinigrin in the digestive tract of rats monoassociated with a human colonic strain of Bacteroides thetaiotaomicron
L Elfoul et al.
FEMS MICROBIOLOGY LETTERS (2001)
Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates
YS Zhang
CARCINOGENESIS (2001)
The chemical diversity and distribution of glucosinolates and isothiocyanates among plants
JW Fahey et al.
PHYTOCHEMISTRY (2001)
Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China
SJ London et al.
LANCET (2000)
Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli
CC Conaway et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2000)
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