相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Exploring the Bacterial Impact on Cholesterol Cycle: A Numerical Study
Melanie Bourgin et al.
FRONTIERS IN MICROBIOLOGY (2020)
Community-driven roadmap for integrated disease maps
Marek Ostaszewski et al.
BRIEFINGS IN BIOINFORMATICS (2019)
Cardiovascular risk factors in non-alcoholic fatty liver disease
Hannes Hagstrom et al.
LIVER INTERNATIONAL (2019)
Serum lipid and lipoprotein levels of middle-aged and elderly Chinese men and women in Shandong Province
Meijian Wang et al.
LIPIDS IN HEALTH AND DISEASE (2019)
Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice
Paul F. Lebeau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
A multi-scale model for low-density lipoprotein cholesterol (LDL-C) regulation in the human body: Application to quantitative systems pharmacology
Masood Khaksar Toroghi et al.
COMPUTERS & CHEMICAL ENGINEERING (2019)
Trajectories of Blood Lipid Concentrations Over the Adult Life Course and Risk of Cardiovascular Disease and All-Cause Mortality: Observations From the Framingham Study Over 35 Years
Meredith S. Duncan et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)
Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging
Eunhui Seo et al.
AGING CELL (2019)
New models of atherosclerosis and multi-drug therapeutic interventions
Andrew Parton et al.
BIOINFORMATICS (2019)
PCSK9 in cholesterol metabolism: from bench to bedside
Allison B. Reiss et al.
CLINICAL SCIENCE (2018)
A mathematical model of the mevalonate cholesterol biosynthesis pathway
Frances Pool et al.
JOURNAL OF THEORETICAL BIOLOGY (2018)
Hypoxic Signaling and Cholesterol Lipotoxicity in Fatty Liver Disease Progression
Oren Tirosh
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Expert curation for building network-based dynamical models: a case study on atherosclerotic plaque formation
Amel Bekkar et al.
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION (2018)
Aging-Induced Biological Changes and Cardiovascular Diseases
James Oluwagbamigbe Fajemiroye et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Oxidative stress, aging, and diseases
Ilaria Liguori et al.
CLINICAL INTERVENTIONS IN AGING (2018)
Retrospective on Cholesterol Homeostasis: The Central Role of Scap
Michael S. Brown et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 87 (2018)
LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature
Uffe Ravnskov et al.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2018)
An Integrated Mathematical Model of Cellular Cholesterol Biosynthesis and Lipoprotein Metabolism
Frances Pool et al.
PROCESSES (2018)
KEGG: new perspectives on genomes, pathways, diseases and drugs
Minoru Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2017)
Investigating cholesterol metabolism and ageing using a systems biology approach
A. E. Morgan et al.
PROCEEDINGS OF THE NUTRITION SOCIETY (2017)
Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel
Brian A. Ference et al.
EUROPEAN HEART JOURNAL (2017)
LDL-C levels in older people: Cholesterol homeostasis and the free radical theory of ageing converge
Mark T. Mc Auley et al.
MEDICAL HYPOTHESES (2017)
Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway
Helen E. Benson et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Modelling the molecular mechanisms of aging
Mark T. Mc Auley et al.
BIOSCIENCE REPORTS (2017)
A Non-invasive Method to Assess Hepatic Acetyl-CoA In Vivo
Rachel J. Perry et al.
CELL METABOLISM (2017)
PCSK9 inhibitors: A new era of lipid lowering therapy
Rahul Chaudhary et al.
WORLD JOURNAL OF CARDIOLOGY (2017)
Computational modelling of atherosclerosis
Andrew Parton et al.
BRIEFINGS IN BIOINFORMATICS (2016)
The Reactome pathway Knowledgebase
Antonio Fabregat et al.
NUCLEIC ACIDS RESEARCH (2016)
Cholesterol metabolism: A review of how ageing disrupts the biological mechanisms responsible for its regulation
A. E. Morgan et al.
AGEING RESEARCH REVIEWS (2016)
Mathematically modelling the dynamics of cholesterol metabolism and ageing
A. E. Morgan et al.
BIOSYSTEMS (2016)
The Success Story of LDL Cholesterol Lowering
Terje R. Pedersen
CIRCULATION RESEARCH (2016)
A deterministic oscillatory model of microtubule growth and shrinkage for differential actions of short chain fatty acids
Josephine Kilner et al.
MOLECULAR BIOSYSTEMS (2016)
The Role of Cholesterol in the Pathogenesis of NASH
George N. Ioannou
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2016)
Aging and computational systems biology
Kathleen M. Mooney et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2016)
Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review
Uffe Ravnskov et al.
BMJ OPEN (2016)
Aging and dyslipidemia: A review of potential mechanisms
Hui-Hui Liu et al.
AGEING RESEARCH REVIEWS (2015)
Low-density lipoprotein cholesterol was inversely associated with 3-year all-cause mortality among Chinese oldest old: Data from the Chinese Longitudinal Healthy Longevity Survey
Yue-Bin Lv et al.
ATHEROSCLEROSIS (2015)
Acetyl-CoA and the regulation of metabolism: mechanisms and consequences
Lei Shi et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
LDL cholesterol still a problem in old age? A Mendelian randomization study
Iris Postmus et al.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2015)
Computationally Modeling Lipid Metabolism and Aging: A Mini-review
Mark T. Mc Auley et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)
Mathematical Modelling of Metabolic Regulation in Aging
Mark T. Mc Auley et al.
METABOLITES (2015)
Vitamin D Metabolism, Mechanism of Action, and Clinical Applications
Daniel D. Bikle
CHEMISTRY & BIOLOGY (2014)
PCSK9 and LDLR degradation: regulatory mechanisms in circulation and in cells
Thomas A. Lagace
CURRENT OPINION IN LIPIDOLOGY (2014)
A mathematical model of the sterol regulatory element binding protein 2 cholesterol biosynthesis pathway
Bonhi S. Bhattacharya et al.
JOURNAL OF THEORETICAL BIOLOGY (2014)
An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway
James Lu et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
Lipid metabolism and hormonal interactions: impact on cardiovascular disease and healthy aging
Mark T. Mc Auley et al.
EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM (2014)
A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway
Alexander Mazein et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Aging affects high-density lipoprotein composition and function
Michael Holzer et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction
Steven Watterson et al.
BIOCHIMIE (2013)
Regulation of cholesterol homeostasis
Mariette Y. M. van der Wulp et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2013)
Intracellular Trafficking and Secretion of VLDL
Samata Tiwari et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
A whole-body mathematical model of cholesterol metabolism and its age-associated dysregulation
Mark T. Mc Auley et al.
BMC SYSTEMS BIOLOGY (2012)
National, regional, and global trends in serum total cholesterol since 1980: systematic analysis of health examination surveys and epidemiological studies with 321 country-years and 3.0 million participants
Farshad Farzadfar et al.
LANCET (2011)
Workflow for generating competing hypothesis from models with parameter uncertainty
David Gomez-Cabrero et al.
INTERFACE FOCUS (2011)
Sterol metabolism and SREBP activation
Ryuichiro Sato
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)
Editing, validating and translating of SBGN maps
Tobias Czauderna et al.
BIOINFORMATICS (2010)
Hypercholesterolemia and 3-hydroxy-3-methylglutaryl coenzyme A reductase regulation in aged female rats
Laura Trapani et al.
EXPERIMENTAL GERONTOLOGY (2010)
Plasma lipoproteins are important components of the immune system
Runlin Han
MICROBIOLOGY AND IMMUNOLOGY (2010)
Acyl-coenzyme A: cholesterol acyltransferases
Ta-Yuan Chang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
The LDL Receptor
Joseph L. Goldstein et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
A continuum receptor model of hepatic lipoprotein metabolism
M. J. Tindall et al.
JOURNAL OF THEORETICAL BIOLOGY (2009)
The Systems Biology Graphical Notation
Nicolas Le Novere et al.
NATURE BIOTECHNOLOGY (2009)
Age-Associated Decrease of High-Density Lipoprotein-Mediated Reverse Cholesterol Transport Activity
Hicham Berrougui et al.
REJUVENATION RESEARCH (2009)
Dynamical modeling of the cholesterol regulatory pathway with Boolean networks
Gwenael Kervizic et al.
BMC SYSTEMS BIOLOGY (2008)
Factores de riesgo cardiovascular. Perspectivas derivadas del Framingham Heart Study
Christopher J. O’Donnell et al.
REVISTA ESPANOLA DE CARDIOLOGIA (2008)
Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2
Hyun Jeong Jeong et al.
JOURNAL OF LIPID RESEARCH (2008)
Age-related HMG-CoA reductase deregulation depends on ROS-induced p38 activation
Valentina Pallottini et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
A dynamical model of lipoprotein metabolism
E. August et al.
BULLETIN OF MATHEMATICAL BIOLOGY (2007)
Liver-specific inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 with antisense oligonucleotides limits atherosclerosis development in apolipoprotein B100-only low-density lipoprotein receptor-/- mice
Thomas A. Bell et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Rat HMGCoA reductase activation in thioacetamide-induced liver injury is related to an increased reactive oxygen species content
V Pallottini et al.
JOURNAL OF HEPATOLOGY (2006)
Intestinal cholesterol absorption is substantially reduced in mice deficient in both ABCA1 and ACAT2
RE Temel et al.
JOURNAL OF LIPID RESEARCH (2005)
Trends in serum lipids and lipoproteins of adults, 1960-2002
MD Carroll et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
3-Hydroxy-3-methylglutaryl coenzyme A reductase deregulation and age-related hypercholesterolemia: A new role for ROS
V Pallottini et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
Dietary restriction counteracts age-related changes in cholesterol metabolism in the rat
MF Mulas et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
AH Payne et al.
ENDOCRINE REVIEWS (2004)
SREBP transcription factors:: master regulators of lipid homeostasis
D Eberlé et al.
BIOCHIMIE (2004)
ACAT2 is localized to Hepatocytes and is the major cholesterol-esterifying enzyme in human liver
P Parini et al.
CIRCULATION (2004)
High-density vs low-density lipoprotein cholesterol as the risk factor for coronary artery disease and stroke in old age
AWE Weverling-Rijnsburger et al.
ARCHIVES OF INTERNAL MEDICINE (2003)
Age-associated decrease in plasma cholesterol and changes in cholesterol metabolism in homozygous watanabe heritable hyperlipidemic rabbits
M Shiomi et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2000)
分享论文
