相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cell and Gene Therapy for Spine Regeneration Mammalian Protein Production Platforms for Overproduction of Therapeutic Proteins and Growth Factors
Ali Mobasheri et al.
NEUROSURGERY CLINICS OF NORTH AMERICA (2020)
TissueGene-C promotes an anti-inflammatory micro-environment in a rat monoiodoacetate model of osteoarthritis via polarization of M2 macrophages leading to pain relief and structural improvement
Hyeonyoul Lee et al.
INFLAMMOPHARMACOLOGY (2020)
A Review on the Current Methods of Chinese Hamster Ovary (CHO) Cells Cultivation for the Production of Therapeutic Protein
Shazid Md. Sharker et al.
Current Drug Discovery Technologies (2020)
Obesity: global epidemiology and pathogenesis
Matthias Blueher
NATURE REVIEWS ENDOCRINOLOGY (2019)
Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine
Jagadeesh Kumar Venkatesan et al.
TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2019)
TGF-β Signaling in Cellular Senescence and Aging-Related Pathology
Kana Tominaga et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development: biochemical markers associated with emerging clinical phenotypes and molecular endotypes
Ali Mobasheri et al.
CURRENT OPINION IN RHEUMATOLOGY (2019)
Glycoengineering in CHO Cells: Advances in Systems Biology
Vijay Tejwani et al.
BIOTECHNOLOGY JOURNAL (2018)
Gene therapy for repair and regeneration of bone and cartilage
Matthew W. Grol et al.
CURRENT OPINION IN PHARMACOLOGY (2018)
Arthritis gene therapy is becoming a reality
Christopher H. Evans et al.
NATURE REVIEWS RHEUMATOLOGY (2018)
Glycoengineering in CHO Cells: Advances in Systems Biology
Vijay Tejwani et al.
BIOTECHNOLOGY JOURNAL (2018)
The Potential of Menstrual Blood-Derived Mesenchymal Stem Cells for Cartilage Repair and Regeneration: Novel Aspects
I. Uzieliene et al.
STEM CELLS INTERNATIONAL (2018)
Extracellular Vesicles in Joint Disease and Therapy
Janneke Boere et al.
FRONTIERS IN IMMUNOLOGY (2018)
Therapeutic glycoprotein production in mammalian cells
Marie-Eve Lalonde et al.
JOURNAL OF BIOTECHNOLOGY (2017)
The changing role of TGFβ in healthy, ageing and osteoarthritic joints
Peter M. van der Kraan
NATURE REVIEWS RHEUMATOLOGY (2017)
The role of metabolism in the pathogenesis of osteoarthritis
Ali Mobasheri et al.
NATURE REVIEWS RHEUMATOLOGY (2017)
Mesenchymal Stem Cells: Time to Change the Name!
Arnold I. Caplan
STEM CELLS TRANSLATIONAL MEDICINE (2017)
Synovitis in osteoarthritis: current understanding with therapeutic implications
Alexander Mathiessen et al.
ARTHRITIS RESEARCH & THERAPY (2017)
Gene therapy for human osteoarthritis: principles and clinical translation
Henning Madry et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2016)
Mesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy - a review
Julien Freitag et al.
BMC MUSCULOSKELETAL DISORDERS (2016)
Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration
Stephen M. Richardson et al.
METHODS (2016)
Mesenchymal stem cells: Identification, phenotypic characterization, biological properties and potential for regenerative medicine through biomaterial micro-engineering of their niche
Julianna Kobolak et al.
METHODS (2016)
Extracellular vesicles - new tool for joint repair and regeneration
Jos Malda et al.
NATURE REVIEWS RHEUMATOLOGY (2016)
Gene Transfer Strategies to Promote Chondrogenesis and Cartilage Regeneration
Gun-Il Im
TISSUE ENGINEERING PART B-REVIEWS (2016)
TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
Masato Morikawa et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Design of a stable cell line producing a recombinant monoclonal anti-TNFα antibody based on a CHO cell line
E. V. Voronina et al.
SPRINGERPLUS (2016)
Adipose, Bone Marrow and Synovial Joint-Derived Mesenchymal Stem Cells for Cartilage Repair
Christopher R. Fellows et al.
FRONTIERS IN GENETICS (2016)
Engineering Translation in Mammalian Cell Factories to Increase Protein Yield: The Unexpected Use of Long Non-Coding SINEUP RNAs
Silvia Zucchelli et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2016)
Immunoregulation by members of the TGFβ superfamily
WanJun Chen et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Cellular and molecular actions of CCN2/CTGF and its role under physiological and pathological conditions
Satoshi Kubota et al.
CLINICAL SCIENCE (2015)
Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Nkemcho Ojeh et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use
V. B. Kraus et al.
OSTEOARTHRITIS AND CARTILAGE (2015)
Proteins improving recombinant antibody production in mammalian cells
Daisuke Nishimiya
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2014)
Improved elongation factor-1 alpha-based vectors for stable high-level expression of heterologous proteins in Chinese hamster ovary cells
Nadezhda A. Orlova et al.
BMC BIOTECHNOLOGY (2014)
Recent advances in mammalian protein production
Ashok D. Bandaranayake et al.
FEBS LETTERS (2014)
Chondrocyte and mesenchymal stem cell-based therapies for cartilage repair in osteoarthritis and related orthopaedic conditions
Ali Mobasheri et al.
MATURITAS (2014)
Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis
Gehua Zhen et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations
Yao-Cheng Lin et al.
NATURE COMMUNICATIONS (2014)
Age-related alterations in TGF beta signaling as a causal factor of cartilage degeneration in osteoarthritis
Peter M. van der Kraan
BIO-MEDICAL MATERIALS AND ENGINEERING (2014)
In vitro growth factor-induced bio engineering of mature articular cartilage
Ilyas M. Khan et al.
BIOMATERIALS (2013)
Expression of recombinant glycoproteins in mammalian cells: towards an integrative approach to structural biology
A. Radu Aricescu et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2013)
Advances in recombinant protein expression for use in pharmaceutical research
Rene Assenberg et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2013)
Angiogenic factors in bone local environment
Shek Man Chim et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2013)
Fibroblast growth factor control of cartilage homeostasis
M. B. Ellman et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2013)
Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
F. Berenbaum
OSTEOARTHRITIS AND CARTILAGE (2013)
Basic science and clinical application of platelet-rich plasma for cartilage defects and osteoarthritis: a review
Y. Zhu et al.
OSTEOARTHRITIS AND CARTILAGE (2013)
Production of Recombinant Therapeutic Proteins in Human Cells: Current Achievements and Future Perspectives
Virginia Picanco-Castro et al.
PROTEIN AND PEPTIDE LETTERS (2013)
Arthritis gene therapy and its tortuous path into the clinic
Christopher H. Evans et al.
TRANSLATIONAL RESEARCH (2013)
The Future of Osteoarthritis Therapeutics: Emerging Biological Therapy
A. Mobasheri
CURRENT RHEUMATOLOGY REPORTS (2013)
Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine
Matthew B. Murphy et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2013)
Advances in Mammalian Cell Line Development Technologies for Recombinant Protein Production
Tingfeng Lai et al.
PHARMACEUTICALS (2013)
The role of synovitis in osteoarthritis pathogenesis
Carla R. Scanzello et al.
BONE (2012)
When versatility matters: activins/inhibins as key regulators of immunity
G. R. Aleman-Muench et al.
IMMUNOLOGY AND CELL BIOLOGY (2012)
Chondrocytes or adult stem cells for cartilage repair: The indisputable role of growth factors
Anne-Marie Freyria et al.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2012)
Human cells: New platform for recombinant therapeutic protein production
Kamilla Swiech et al.
PROTEIN EXPRESSION AND PURIFICATION (2012)
The Role of Growth Factors in Cartilage Repair
Lisa A. Fortier et al.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2011)
The Role of Connective Tissue Growth Factor (CTGF/CCN2) in Skeletogenesis
John A. Arnott et al.
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION (2011)
Transplanted articular chondrocytes co-overexpressing IGF-I and FGF-2 stimulate cartilage repair in vivo
Patrick Orth et al.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY (2011)
Effects on Proliferation and Differentiation of Multipotent Bone Marrow Stromal Cells Engineered to Express Growth Factors for Combined Cell and Gene Therapy
Fernando A. Fierro et al.
STEM CELLS (2011)
Intraarticular Injection of Heparin-Binding Insulin-like Growth Factor 1 Sustains Delivery of Insulin-like Growth Factor 1 to Cartilage Through Binding to Chondroitin Sulfate
Rachel E. Miller et al.
ARTHRITIS AND RHEUMATISM (2010)
The role of biomechanics in the initiation and progression of OA of the knee
Martin Englund
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2010)
Cell Engineering and Cultivation of Chinese Hamster Ovary (CHO) Cells
Takeshi Omasa et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2010)
Growth factor regulation of proliferation and survival of multipotential stromal cells
Melanie Rodrigues et al.
STEM CELL RESEARCH & THERAPY (2010)
Joint homeostasis, restoration, and remodeling in osteoarthritis
Rik J. U. Lories
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2008)
Growth factor delivery methods in the management of sports injuries: the state of play
L. Creaney et al.
BRITISH JOURNAL OF SPORTS MEDICINE (2008)
Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis
Michael B. Ellman et al.
GENE (2008)
Concepts in gene therapy for cartilage repair
Andre F. Steinert et al.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2008)
Growth factors and cytokines in wound healing
Stephan Barrientos et al.
WOUND REPAIR AND REGENERATION (2008)
Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor β-induced osteophytes
E. N. Blaney Davidson et al.
ARTHRITIS AND RHEUMATISM (2007)
Application of destabilizing sequences on selection marker for improved recombinant protein productivity in CHO-DG44
Say Kong Ng et al.
METABOLIC ENGINEERING (2007)
Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives
Lucia Baldi et al.
BIOTECHNOLOGY LETTERS (2007)
The role of TGF-β superfamily during T cell development:: new insights
P. Licona-Limon et al.
IMMUNOLOGY LETTERS (2007)
Role of transforming growth factor-β in hematologic malignancies
Mei Dong et al.
BLOOD (2006)
Gene therapeutic approaches-transfer in vivo
C. H. Evans et al.
ADVANCED DRUG DELIVERY REVIEWS (2006)
A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair
M. B. Schmidt et al.
OSTEOARTHRITIS AND CARTILAGE (2006)
Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo
G Kaul et al.
JOURNAL OF GENE MEDICINE (2006)
Transient gene expression in suspension HEK-293 cells: Application to large-scale protein production
L Baldi et al.
BIOTECHNOLOGY PROGRESS (2005)
Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I)
H Madry et al.
GENE THERAPY (2005)
Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2
M Cucchiarini et al.
MOLECULAR THERAPY (2005)
Fibroblast growth factor signaling during early vertebrate development
RT Böttcher et al.
ENDOCRINE REVIEWS (2005)
Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity
ENB Davidson et al.
ARTHRITIS RESEARCH & THERAPY (2005)
Osteoarthritis gene therapy
CH Evans et al.
GENE THERAPY (2004)
Risk factors for osteoarthritis -: Understanding joint vulnerability
DT Felson
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2004)
Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis
AB Blom et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
Activin A and follistatin in systemic inflammation
KL Jones et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2004)
Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system
H Madry et al.
JOURNAL OF GENE MEDICINE (2003)
Stem cell therapy in a caprine model of osteoarthritis
JM Murphy et al.
ARTHRITIS AND RHEUMATISM (2003)
Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis
A Scharstuhl et al.
ARTHRITIS AND RHEUMATISM (2003)
Recombinant protein expression for therapeutic applications
DC Andersen et al.
CURRENT OPINION IN BIOTECHNOLOGY (2002)
Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis
JM Murphy et al.
ARTHRITIS AND RHEUMATISM (2002)
Gene therapy - Future therapies in osteoarthritis
DD Frisbie et al.
VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE (2001)
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation
AC Bakker et al.
OSTEOARTHRITIS AND CARTILAGE (2001)
The family of bone morphogenetic proteins
P Ducy et al.
KIDNEY INTERNATIONAL (2000)
Epidermal growth factor and keratinocyte growth factor differentially regulate epidermal migration, growth, and differentiation
S Gibbs et al.
WOUND REPAIR AND REGENERATION (2000)