期刊
ISCIENCE
卷 23, 期 11, 页码 -出版社
CELL PRESS
DOI: 10.1016/j.isci.2020.101716
关键词
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资金
- ANR TRANSCAN [ANR-18-CE35-0009]
- MAVA Foundation
- Rotary Club Les Sables d'Olonne
- CNRS International Associated Laboratory Grant
- ARC Linkage [LP170101105]
- Deakin SEBE_RGS_2019
- Australian Research Council [LP170101105] Funding Source: Australian Research Council
- Agence Nationale de la Recherche (ANR) [ANR-18-CE35-0009] Funding Source: Agence Nationale de la Recherche (ANR)
Cellular cheating leading to cancers exists in all branches of multicellular life, favoring the evolution of adaptations to avoid or suppress malignant progression, and/or to alleviate its fitness consequences. Ecologists have until recently largely neglected the importance of cancer cells for animal ecology, presumably because they did not consider either the potential ecological or evolutionary consequences of anticancer adaptations. Here, we review the diverse ways in which the evolution of anticancer adaptations has significantly constrained several aspects of the evolutionary ecology of multicellular organisms at the cell, individual, population, species, and ecosystem levels and suggest some avenues for future research.
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