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CIRCULATION JOURNAL (2010)
Angiotensin-(1-7) Prevents Cardiomyocyte Pathological Remodeling Through a Nitric Oxide/Guanosine 3 ',5 '-Cyclic Monophosphate-Dependent Pathway
Eneas R. M. Gomes et al.
HYPERTENSION (2010)
Renal ACE2 expression and activity is unaltered during established hypertension in adult SHRSP and TGR(mREN2)27
Jelena Kamilic et al.
HYPERTENSION RESEARCH (2010)
Exercise training normalizes ACE and ACE2 in the brain of rabbits with pacing-induced heart failure
Sumit Kar et al.
JOURNAL OF APPLIED PHYSIOLOGY (2010)
Tissue-specific Pattern of Angiotensin-converting Enzyme 2 Expression in Rat Pancreas
H. J. Fang et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2010)
Physiological Genomics Identifies Estrogen-Related Receptor alpha as a Regulator of Renal Sodium and Potassium Homeostasis and the Renin-Angiotensin Pathway
Annie M. Tremblay et al.
MOLECULAR ENDOCRINOLOGY (2010)
The angiotensin-converting enzyme 2 in tumor growth and tumor-associated angiogenesis in non-small cell lung cancer
Yun Feng et al.
ONCOLOGY REPORTS (2010)
Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent
Jun Liu et al.
Biology of Sex Differences (2010)
Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia
Hong Peng Jia et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Soluble Angiotensin-Converting Enzyme 2 in Human Heart Failure: Relation With Myocardial Function and Clinical Outcomes
Slava Epelman et al.
JOURNAL OF CARDIAC FAILURE (2009)
Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor
Kailang Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
Sandrine Belouzard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway
Vijay Koka et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides
Patricia E. Gallagher et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet
Manisha Gupte et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)
Functional angiotensin-converting enzyme 2 is expressed in human cardiac myofibroblasts
Jodie L. Guy et al.
EXPERIMENTAL PHYSIOLOGY (2008)
RNA interference shows interactions between mouse brainstem angiotensin AT1 receptors and angiotensin-converting enzyme 2
Zhanyi Lin et al.
EXPERIMENTAL PHYSIOLOGY (2008)
Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart
Paul J. Garabelli et al.
EXPERIMENTAL PHYSIOLOGY (2008)
Genetically altered animal models for Mas and angiotensin-(1-7)
Natalia Alenina et al.
EXPERIMENTAL PHYSIOLOGY (2008)
The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice
Yumiko Imai et al.
EXPERIMENTAL PHYSIOLOGY (2008)
Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease
Heather N. Reich et al.
KIDNEY INTERNATIONAL (2008)
The antithrombotic effect of angiotensin-(1-7) involves mas-mediated NO release from platelets
Rodrigo Araujo Fraga-Silva et al.
MOLECULAR MEDICINE (2008)
Role of the renin-angiotensin system in vascular inflammation
Chiara Marchesi et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Pathology of experimental SARS coronavirus infection in cats and ferrets
J. M. A. Van den Brand et al.
VETERINARY PATHOLOGY (2008)
Loss of angiotensin-converting enzyme 2 leads to impaired glucose homeostasis in mice
Ming-Jia Niu et al.
ENDOCRINE (2008)
Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain
Daniel W. Lambert et al.
FEBS LETTERS (2008)
Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells
Walkyria O. Sampaio et al.
HYPERTENSION (2007)
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
T. Fernandes-Alnemri et al.
CELL DEATH AND DIFFERENTIATION (2007)
Angiotensin-converting enzyme converts amyloid β-protein 1-42 (Aβ1-42) to Aβ1-40, and its inhibition enhances brain aβ deposition
Kun Zou et al.
JOURNAL OF NEUROSCIENCE (2007)
Angiotensin converting enzyme 2 is primarily epithelial and is developmentally regulated in the mouse lung
Renda Soylemez Wiener et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Angiotensin-converting enzyme 2 in acute respiratory distress syndrome
Y. Imai et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Angiotensin II and its receptor subtypes in the human retina
Preenie deS. Senanayake et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats
Masanobu Yamazato et al.
HYPERTENSION (2007)
Mass-spectrometric identification of a novel angiotensin peptide in human plasma
Vera Jankowski et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system
Marc F. Doobay et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)
Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways
Walkyria Oliveira Sampaio et al.
HYPERTENSION (2007)
Lessons from SARS: control of acute lung failure by the SARS receptor ACE2
Keiji Kuba et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice
Susan B. Gurley et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Chronic angiotensin-(1-7) prevents cardiac fibrosis in DOCA-salt model of hypertension
Justin L. Grobe et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Age- and gender-related difference of ACE2 expression in rat lung
XD Xie et al.
LIFE SCIENCES (2006)
Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes
PE Gallagher et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2
G Paizis et al.
GUT (2005)
Structure of SARS coronavirus spike receptor-binding domain complexed with receptor
F Li et al.
SCIENCE (2005)
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
K Kuba et al.
NATURE MEDICINE (2005)
Membrane-associated zinc peptidase families: comparing ACE and ACE2
JL Guy et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)
Angiotensin-converting enzyme 2 protects from severe acute lung failure
Y Imai et al.
NATURE (2005)
Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents
F Gembardt et al.
PEPTIDES (2005)
Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry
H Hofmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2
CM Ferrario et al.
CIRCULATION (2005)
Myocardial infarction increases ACE2 expression in rat and humans
LM Burrell et al.
EUROPEAN HEART JOURNAL (2005)
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors
Y Ishiyama et al.
HYPERTENSION (2004)
ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis
P Towler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A model of the ACE2 structure and function as a SARS-CoV receptor
P Prabakaran et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis
GC Douglas et al.
ENDOCRINOLOGY (2004)
Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor
H Hofmann et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Identification of angiotensin converting enzyme 2 in the rodent retina
C Tikellis et al.
CURRENT EYE RESEARCH (2004)
Renal ACE2 expression in human kidney disease
AT Lely et al.
JOURNAL OF PATHOLOGY (2004)
Structure-based discovery of a novel angiotensin converting enzyme 2 inhibitor
MJ Huentelman et al.
HYPERTENSION (2004)
ACE2: from vasopeptidase to SARS virus receptor
AJ Turner et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis
I Hamming et al.
JOURNAL OF PATHOLOGY (2004)
ACE2 gene expression is up-regulated in the human failing heart
Andrew B. Goulter et al.
BMC MEDICINE (2004)
Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in rats
RAS Santos et al.
PHYSIOLOGICAL GENOMICS (2004)
Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism
GI Rice et al.
BIOCHEMICAL JOURNAL (2004)
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
WH Li et al.
NATURE (2003)
Angiotensin-converting enzyme-2 (ACE2): Comparative modeling of the active site, specificity requirements, and chloride dependence
JL Guy et al.
BIOCHEMISTRY (2003)
Endothelial activation by angiotensin II through NFκB and p38 pathways:: Involvement of NFκB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin
A Costanzo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2003)
The genome sequence of the SARS-associated coronavirus
MA Marra et al.
SCIENCE (2003)
Characterization of a novel coronavirus associated with severe acute respiratory syndrome
PA Rota et al.
SCIENCE (2003)
A novel coronavirus associated with severe acute respiratory syndrome
TG Ksiazek et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Novel peptide inhibitors of angiotensin-converting enzyme 2
LL Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
R Natesh et al.
NATURE (2003)
Angiotensin-I-converting enzyme and its relatives
JF Riordan
GENOME BIOLOGY (2003)
Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors
NA Dales et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Angiotensin converting enzyme insertion /deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome
RP Marshall et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)
Angiotensin-converting enzyme 2 is an essential regulator of heart function
MA Crackower et al.
NATURE (2002)
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
C Vickers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats
AE Loot et al.
CIRCULATION (2002)
Angiotensin-(1-7): Cardioprotective effect in myocardial ischemia/reperfusion
AJ Ferreira et al.
HYPERTENSION (2001)
Pro-inflammatory programmed cell death
BT Cookson et al.
TRENDS IN MICROBIOLOGY (2001)
A human homolog of angiotensin-converting enzyme - Cloning and functional expression as a captopril-insensitive carboxypeptidase
SR Tipnis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
M Donoghue et al.
CIRCULATION RESEARCH (2000)
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