Poly caprolactone/titanium dioxide nanofiber coating on AM50 alloy for biomedical application

Poly caprolactone (PCL) and Poly caprolactone/TiO2 (PCL/TiO2) composite nanofiber with different weight percentage compositions (2 wt%, 4 wt% and 6 wt%) of TiO2 were prepared and coated over AM50 alloy using electrospinning technique. The surface morphology and elemental composition result confirms that the PCL/TiO2 composite nanofiber fiber were successfully electrospun on the surface of AM50 alloy. The degradation behavior of PCL and PCL/6 wt% TiO2 coated AM50 alloy was studied by immersing in Simulated Body Fluid (SBF) solution. The electrochemical and cell proliferation studies reveals that the cellular behavior of PCL and PCL/6 wt% TiO2 composite nanofiber exhibited good support for cell proliferation with enhanced corrosion resistance of AM50 alloy in SBF solution. (C) 2020 Chongqing University. Publishing services provided by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.

Automated summary

The study involved the preparation of PCL/TiO2 composite nanofiber on AM50 alloy surface using electrospinning technique. The results showed that the AM50 alloy coated with PCL/6 wt% TiO2 exhibited excellent cellular proliferation support and corrosion resistance in SBF solution.