期刊
WORLD JOURNAL OF CLINICAL CASES
卷 8, 期 18, 页码 3934-3941出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.12998/wjcc.v8.i18.3934
关键词
COVID-19; SARS-CoV-2; Diarrhea; Colorectal cancer; Inflammatory bowel disease; Stool tests
资金
- National Natural Science Foundation of China [81970494]
Coronavirus disease-2019 (COVID-19) has so far caused hundreds of mortalities worldwide. Although respiratory symptoms are the main complication in COVID-19 patients, the disease is also associated with gastrointestinal problems, with diarrhea, nausea, and vomiting being primary COVID-19 symptoms. Thus, cancer and inflammatory bowel disease (IBD) management, stool viral tests, and virus exposure are major concerns in the context of COVID-19 epidemic. In patients with colorectal cancer and IBD, the colonic mucosa exhibits elevated angiotensin-converting enzyme 2 receptor levels, enhancing COVID-19 susceptibility. In some cases, positive viral stool tests may be the only indicator of infection at admission or after leaving quarantine. Without supplemental stool tests, the risk of undetected COVID-19 transmission is high. Moreover, viral exposure during the regular or emergency endoscopic examination should be avoided. We carefully discuss key gastrointestinal concerns with regard to COVID-19 and call for more attention to such problems.
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