期刊
MICROBIAL BIOTECHNOLOGY
卷 14, 期 1, 页码 18-21出版社
WILEY
DOI: 10.1111/1751-7915.13674
关键词
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资金
- China National Key Research and Development Program [2018YFA0900200]
- National Natural Science Foundation of China [31870859, 21761132013, 31771886, 31971170]
Microbial fermentations have been used to produce various products for many years, but they face challenges such as energy consumption, water shortage and microbial contaminations. Future industrial fermentations should be more effective with the above issues reasonably addressed.
Microbial fermentations produce chemicals, materials, biofuels, foods and medicines for many years. The processes are less competitive compared to chemical industries. To increase its competitiveness, technologies must be developed to address the following issues including fresh water shortage, heavy energy consumption, microbial contaminations, complexity of sterile operations, poor oxygen utilization in the cultures, food-related ingredients as substrates, low substrate to product conversion efficiency, difficult cells and broth separation, large amount of wastewater, discontinuous processes, heavy labour involvements and expensive bioreactors. Future industrial fermentations should be more effective with the above issues reasonably addressed. Recently, extremophilic bacteria have well addressed the above issues for future fermentation.
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