相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Improving the Efficacy of Liver Cancer Immunotherapy: The Power of Combined Preclinical and Clinical Studies
Gen-Sheng Feng et al.
HEPATOLOGY (2021)
The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma
Haiyu Wang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Fibroblasts in urothelial bladder cancer define stroma phenotypes that are associated with clinical outcome
Artur Mezheyeuski et al.
SCIENTIFIC REPORTS (2020)
Fibrosis and cancer: A strained relationship
Bram Piersma et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2020)
Hyperbranched lipoid-based lipid nanoparticles for bidirectional regulation of collagen accumulation in liver fibrosis
Jian-Bin Qiao et al.
JOURNAL OF CONTROLLED RELEASE (2020)
Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma
Richard S. Finn et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
The role of fibroblast activation protein in health and malignancy
Allison A. Fitzgerald et al.
CANCER AND METASTASIS REVIEWS (2020)
Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
Ying Shen et al.
CANCER CELL (2020)
In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles
Leonard Kaps et al.
CELLS (2020)
A framework for advancing our understanding of cancer-associated fibroblasts
Erik Sahai et al.
NATURE REVIEWS CANCER (2020)
Roles of Fibroblast Activation Protein and Hepatocyte Growth Factor Expressions in Angiogenesis and Metastasis of Gastric Cancer
Li-Ming Gao et al.
PATHOLOGY & ONCOLOGY RESEARCH (2019)
Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats
Sabine Klein et al.
SCIENTIFIC REPORTS (2019)
The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma
Jacopo Baglieri et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
An integrin-based nanoparticle that targets activated hepatic stellate cells and alleviates liver fibrosis
Yanping Li et al.
JOURNAL OF CONTROLLED RELEASE (2019)
A Phase 2 Study of Galunisertib (TGF-β1 Receptor Type I Inhibitor) and Sorafenib in Patients With Advanced Hepatocellular Carcinoma
R. K. Kelley et al.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2019)
Multiplex quantitative analysis of cancer-associated fibroblasts and immunotherapy updates outcome in metastatic melanoma
Pok Fai Wong et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy
Tongyan Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
The role of collagen in cancer: from bench to bedside
Shuaishuai Xu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2019)
A global view of hepatocellular carcinoma: trends, risk, prevention and management
Ju Dong Yang et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)
Ramucirumab after sorafenib in patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations (REACH-2): a randomised, double-blind, placebo-controlled, phase 3 trial
Andrew X. Zhu et al.
LANCET ONCOLOGY (2019)
TGF-β as Multifaceted Orchestrator in HCC Progression: Signaling, EMT, Immune Microenvironment, and Novel Therapeutic Perspectives
Francesco Dituri et al.
SEMINARS IN LIVER DISEASE (2019)
pPB Peptide-Mediated siRNA-Loaded Stable Nucleic Acid Lipid Nanoparticles on Targeting Therapy of Hepatic Fibrosis
Zongxiang Jia et al.
MOLECULAR PHARMACEUTICS (2018)
Pharmacokinetics of a sustained release formulation of PDGF beta-receptor directed carrier proteins to target the fibrotic liver
F. van Dijk et al.
JOURNAL OF CONTROLLED RELEASE (2018)
Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial
Masatoshi Kudo et al.
LANCET (2018)
Liver fibrosis: Direct antifibrotic agents and targeted therapies
Detlef Schuppan et al.
MATRIX BIOLOGY (2018)
Cell type-specific pharmacological kinase inhibition for cancer chemoprevention
Manjeet Deshmukh et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)
Cancer-associated fibroblasts induce PDL1+neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma
Yusheng Cheng et al.
CELL DEATH & DISEASE (2018)
The role of osteopontin in the progression of solid organ tumour
Hailin Zhao et al.
CELL DEATH & DISEASE (2018)
The immune contexture of hepatocellular carcinoma predicts clinical outcome
Friedrich Foerster et al.
SCIENTIFIC REPORTS (2018)
Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development
Yun-Chieh Sung et al.
THERANOSTICS (2018)
The Expression of FAP in Hepatocellular Carcinoma Cells is Induced by Hypoxia and Correlates with Poor Clinical Outcomes
Baojia Zou et al.
JOURNAL OF CANCER (2018)
Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis
Isabel Fabregat et al.
FRONTIERS IN ONCOLOGY (2018)
Role of Wnt/β-catenin signaling in hepatocellular carcinoma, pathogenesis, and clinical significance
Ahmed M. Khalaf et al.
JOURNAL OF HEPATOCELLULAR CARCINOMA (2018)
Origin of cancer-associated fibroblasts and tumor-associated macrophages in humans after sex-mismatched bone marrow transplantation
Masako Kurashige et al.
COMMUNICATIONS BIOLOGY (2018)
The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury
Xin M. Wang et al.
IMMUNOLOGY AND CELL BIOLOGY (2017)
Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases
Y. Wang et al.
MOLECULAR NEUROBIOLOGY (2017)
SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles
Nadine Leber et al.
JOURNAL OF CONTROLLED RELEASE (2017)
The nature and biology of basement membranes
Ambra Pozzi et al.
MATRIX BIOLOGY (2017)
Osteopontin at the Crossroads of Inflammation and Tumor Progression
Luigi Mario Castello et al.
MEDIATORS OF INFLAMMATION (2017)
Prognostic significance of tumor-associated macrophages in breast cancer: a meta-analysis of the literature
Xixi Zhao et al.
ONCOTARGET (2017)
Tumor Microenvironment and Differential Responses to Therapy
Eishu Hirata et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice
Nina D. Thiele et al.
SCIENTIFIC REPORTS (2017)
Progress of antibody-based inhibitors of the HGF-cMET axis in cancer therapy
Ki-Hyun Kim et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2017)
Integrin alpha v beta 6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis
Zhen-Wei Peng et al.
HEPATOLOGY (2016)
FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling
Xuguang Yang et al.
CANCER RESEARCH (2016)
Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
Philippe Gascard et al.
GENES & DEVELOPMENT (2016)
Prognostic value of polarized macrophages in patients with hepatocellular carcinoma after curative resection
Qing-Hua Shu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2016)
Role of epithelial to mesenchymal transition in hepatocellular carcinoma
Gianluigi Giannelli et al.
JOURNAL OF HEPATOLOGY (2016)
Tumor-associated fibroblasts predominantly come from local and not circulating precursors
Ainhoa Arina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Cancer-associated fibroblasts in hepatocellular carcinoma
Norio Kubo et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2016)
Activated hepatic stellate cells promote liver cancer by induction of myeloid-derived suppressor cells through cyclooxygenase-2
Yaping Xu et al.
ONCOTARGET (2016)
Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling
Feng Liu et al.
SCIENTIFIC REPORTS (2016)
Novel insights into the function and dynamics of extracellular matrix in liver fibrosis
Morten A. Karsdal et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2015)
Hepatic stellate cells: central modulators of hepatic carcinogenesis
Alexandra I. Thompson et al.
BMC GASTROENTEROLOGY (2015)
Specific hepatic delivery of procollagen 1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis
Carolina Jimenez Calvente et al.
HEPATOLOGY (2015)
Hepatic stellate cell and monocyte interaction contributes to poor prognosis in hepatocellular carcinoma
Juling Ji et al.
HEPATOLOGY (2015)
Combination cancer immunotherapy and new immunomodulatory targets
Kathleen M. Mahoney et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
TIMP-1 activated carcinoma-associated fibroblasts inhibit tumor apoptosis by activating SDF1/CXCR4 signaling in hepatocellular carcinoma
Tao Song et al.
ONCOTARGET (2015)
In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles
Leonard Kaps et al.
ADVANCED HEALTHCARE MATERIALS (2015)
Role of activated hepatic stellate cells in proliferation and metastasis of hepatocellular carcinoma
Nan Lin et al.
HEPATOLOGY RESEARCH (2015)
Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers
Thomas K. Kilvaer et al.
PLOS ONE (2015)
Roles of Tumor Microenvironment in Hepatocelluar Carcinoma
Haeng R. Seo
CURRENT CANCER THERAPY REVIEWS (2015)
Non-collagenous ECM proteins in blood vessel morphogenesis and cancer
Vassiliki Kostourou et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
Berna C. Oezdemir et al.
CANCER CELL (2014)
Activated Human Hepatic Stellate Cells Promote Growth of Human Hepatocellular Carcinoma in a Subcutaneous Xenograft Nude Mouse Model
Zhi-min Geng et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2014)
Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells
Shanshan Wan et al.
GASTROENTEROLOGY (2014)
Interferon gamma peptidomimetic targeted to hepatic stellate cells ameliorates acute and chronic liver fibrosis in vivo
Ruchi Bansal et al.
JOURNAL OF CONTROLLED RELEASE (2014)
Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever
Vinicio Carloni et al.
LIVER INTERNATIONAL (2014)
Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma
H. Wang et al.
CELL DEATH & DISEASE (2014)
Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs
Fiona M. Keane et al.
FEBS OPEN BIO (2014)
Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation
Kaori Kuramitsu et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Targeting the HGF/c-MET Pathway in Hepatocellular Carcinoma
Lipika Goyal et al.
CLINICAL CANCER RESEARCH (2013)
Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma
Virginia Hernandez-Gea et al.
GASTROENTEROLOGY (2013)
Sublethal Heat Treatment Promotes Epithelial-Mesenchymal Transition and Enhances the Malignant Potential of Hepatocellular Carcinoma
Shuhei Yoshida et al.
HEPATOLOGY (2013)
Evolving therapies for liver fibrosis
Detlef Schuppan et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion
Bastian Hoechst et al.
JOURNAL OF HEPATOLOGY (2013)
Enhanced Effectivity of an ALK5-Inhibitor after Cell-Specific Delivery to Hepatic Stellate Cells in Mice with Liver Injury
Marike Marjolijn van Beuge et al.
PLOS ONE (2013)
TIMP-1 Promotes Accumulation of Cancer Associated Fibroblasts and Cancer Progression
Yixuan Gong et al.
PLOS ONE (2013)
Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
Christine Feig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cationic Nanohydrogel Particles as Potential siRNA Carriers for Cellular Delivery
Lutz Nuhn et al.
ACS NANO (2012)
Identification of osteopontin as a novel marker for early hepatocellular carcinoma
Sufen Shang et al.
HEPATOLOGY (2012)
Effects of interferon-gamma liposomes targeted to platelet-derived growth factor receptor-beta on hepatic fibrosis in rats
Feng Li et al.
JOURNAL OF CONTROLLED RELEASE (2012)
Selective Targeting of Interferon γ to Stromal Fibroblasts and Pericytes as a Novel Therapeutic Approach to Inhibit Angiogenesis and Tumor Growth
Ruchi Bansal et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
Michael Quante et al.
CANCER CELL (2011)
Novel Engineered Targeted Interferon-gamma Blocks Hepatic Fibrogenesis in Mice
Ruchi Bansal et al.
HEPATOLOGY (2011)
Hepatic Stellate Cells: Partners in Crime for Liver Metastases?
Ningling Kang et al.
HEPATOLOGY (2011)
Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice
Wenxiu Zhao et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
HCC and angiogenesis: possible targets and future directions
Andrew X. Zhu et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2011)
Focal Adhesion Assembly in Myofibroblasts Fosters a Microenvironment that Promotes Tumor Growth
Ningling Kang et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Targeting the transforming growth factor-beta signaling pathway in human cancer
Nagathihalli S. Nagaraj et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)
Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Dead or Alive?
Yury Popov et al.
GASTROENTEROLOGY (2010)
Reduction of Advanced Liver Fibrosis by Short-Term Targeted Delivery of an Angiotensin Receptor Blocker to Hepatic Stellate Cells in Rats
Montserrat Moreno et al.
HEPATOLOGY (2010)
Tumor-targeted intracellular delivery of anticancer drugs through the mannose-6-phosphate/insulin-like growth factor II receptor
Jai Prakash et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
The polarization of immune cells in the tumour environment by TGFβ
Richard A. Flavell et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Peritumoral Activated Hepatic Stellate Cells Predict Poor Clinical Outcome in Hepatocellular Carcinoma After Curative Resection
Min-Jie Ju et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2009)
Pharmacological Inhibition of Integrin αvβ3 Aggravates Experimental Liver Fibrosis and Suppresses Hepatic Angiogenesis
Eleonora Patsenker et al.
HEPATOLOGY (2009)
A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4+CD25+Foxp3+ T cells
Bastian Hoechst et al.
GASTROENTEROLOGY (2008)
Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis
Kojiro Taura et al.
GASTROENTEROLOGY (2008)
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans
Alessia Omenetti et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone
Yasushi Sato et al.
NATURE BIOTECHNOLOGY (2008)
Phase II clinical trial of the epothilone B analog, ixabepilone, in patients with non-small-cell lung cancer whose tumors have failed first-line platinum-based chemotherapy
Johan Vansteenkiste et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Final results of a multi-center, double-blind, randomized, placebo-controlled phase II study to assess the efficacy of MAGE-A3 immunotherapeutic as adjuvant therapy in stage IB/II non-small cell lung cancer (NSCLC)
J. Vansteenkiste et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats
Joanna E. Adrian et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)
Targeting 15d-prostaglandin J2 to hepatic stellate cells:: Two options evaluated
Werner I. Hagens et al.
PHARMACEUTICAL RESEARCH (2007)
The prognostic significance of preoperative plasma levels of osteopontin in patients with hepatocellular carcinoma
Hui Zhang et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2006)
Hepatitis B virus promotes angiopoietin-2 expression in liver tissue -: Role of HBV X protein
Paloma Sanz-Cameno et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Elevated plasma osteopontin levels in patients with hepatocellular carcinoma
Jin Kim et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2006)
Mannose-6-phosphate/insulin-like growth Factor-II receptors may represent a target for the selective delivery of mycophenolic acid to fibrogenic cells
Rick Greupink et al.
PHARMACEUTICAL RESEARCH (2006)
Correlation between genomic DNA copy number alterations and transcriptional expression in hepatitis B virus-associated hepatocellular carcinoma
Jian Huang et al.
FEBS LETTERS (2006)
Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems
JE Adrian et al.
JOURNAL OF HEPATOLOGY (2006)
Hepatocyte growth factor and c-Met expression in rat and human liver fibrosis
T Cramer et al.
LIVER INTERNATIONAL (2004)
Stromal fibroblasts in cancer initiation and progression
NA Bhowmick et al.
NATURE (2004)
Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma
T Torimura et al.
JOURNAL OF HEPATOLOGY (2004)
The preferential homing of a platelet derived growth factor receptor-recognizing macromolecule to fibroblast-like cells in fibrotic tissue
L Beljaars et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Overexpression of osteopontin is associated with intrahepatic metastasis, early recurrence, and poorer prognosis of surgically resected hepatocellular carcinoma
HW Pan et al.
CANCER (2003)
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
QH Ye et al.
NATURE MEDICINE (2003)
Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis
E Olaso et al.
HEPATOLOGY (2003)
Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis
RT Aimes et al.
THROMBOSIS AND HAEMOSTASIS (2003)
Stromal antigen targeting by a humanised monoclonal antibody:: An early phase II trial of sibrotuzamab in patients with metastatic colorectal cancer
RD Hofheinz et al.
ONKOLOGIE (2003)
Angiopoietin switching regulates angiogenesis and progression of human hepatocellular carcinoma
K Sugimachi et al.
JOURNAL OF CLINICAL PATHOLOGY (2003)
Overexpression of osteopontin in hepatocellular carcinoma
M Gotoh et al.
PATHOLOGY INTERNATIONAL (2002)
Matrix as a modulator of hepatic fibrogenesis
D Schuppan et al.
SEMINARS IN LIVER DISEASE (2001)
Successful targeting to rat hepatic stellate cells using albumin modified with cyclic peptides that recognize the collagen type VI receptor
L Beljaars et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Targeted disruption of mouse fibroblast activation protein
J Niedermeyer et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)