期刊
ADVANCES IN WOUND CARE
卷 10, 期 11, 页码 623-640出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/wound.2020.1219
关键词
bacterial cellulose; functional modification; wound dressing; wound healing
类别
资金
- National Natural Science Foundation of China [31700829, 51973018, 51773018]
- Key Research and Development Projects of People's Liberation Army [BWS17J036]
- Natural Science Foundation of Jiangxi Province of China [20192ACB20033]
- Haiyan Project of Lianyungang [KD2019lyghy001]
Bacterial cellulose (BC) is a natural polymer with good biological activity and unique physical, chemical, and biological properties, suitable for wound dressings. Different methods have been adopted to modify BC for optimizing its biocompatibility and antimicrobial activity, promoting wound healing. BC-based dressings have been applied in various types of wounds with remarkable therapeutic effects.
Significance: Wound dressings are frequently used for wound covering and healing. Ideal wound dressings should provide a moist environment for wounds and actively promote wound healing and skin recovery. The materials used as ideal wound dressings should possess specific properties, thus accelerating skin tissue regeneration process. Recent Advances: Bacterial cellulose (BC) is a natural polymer synthesized by some bacteria. As a kind of natural biopolymer, BC shows good biological activity, biodegradability, and biological adaptability. It has many unique physical, chemical, and biological properties, such as ultrafine nanofiber network, high crystallinity, high water absorption and retention capacity, and high tensile strength and elastic modulus. These excellent properties of BC have laid the foundation for its application as dressing in wound healing. Critical Issues: To optimize the biocompatibility and antimicrobial activity of BC, different methods including microbial fermentation, physical modification, chemical modification, and compound modification have been adopted to modify BC to ensure a better application in wound healing. BC-based wound dressings have been applied in infected wounds, acute traumatic injuries, burns, and diabetic wounds, showing remarkable therapeutic effects on promoting wound healing. Furthermore, there have been some commercial BC-based dressings and they have been utilized in clinical practice. Future Directions: Because of its excellent physicochemical characteristics and biological properties, BC shows high clinical value to be used as a wound dressing for skin tissue regeneration.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据