4.5 Article

Biomimetic Approaches Towards the Synthesis of Complex Dimeric Natural Products

期刊

CURRENT PHARMACEUTICAL DESIGN
卷 22, 期 12, 页码 1628-1657

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1381612822666160101123106

关键词

Biomimetic; dimer; natural product; total synthesis

资金

  1. Engineering and Physical Sciences Research Council [1225401] Funding Source: researchfish

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We present a selection of elegant and diverse biomimetic syntheses of complex natural product dimers. The dimerisation pathways discussed encompass the most prevalent strategies, including: Diels-Alder, Aldol, Mannich, conjugate addition, oxidative, radical and photochemical approaches; each underpinned through rational biosynthetic speculation.

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