期刊
CURRENT PHARMACEUTICAL DESIGN
卷 22, 期 10, 页码 1361-1370出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1381612822666160125114144
关键词
Opioid and cannabinoid receptors; obesity; anorexia nervosa; bulimia nervosa; orexigenic and anorexigenic peptides
资金
- Medical University of Lodz [503/1-156-02/503-01]
- POLONIUM European Agreement (France-Poland exchange program) [30827ZB]
Energy intake and expenditure are regulated by a complex network of neurochemical systems. The results of numerous studies have provided information about receptors involved, the sites of action within the brain and interactions between various systems, including opioid and cannabinoid, in regulation of energy balance. This review summarizes our present knowledge on the opioid and cannabinoid system appetite and satiety pathways. The involvement of the three main types of opioid receptors (MOR, DOR and KOR) and CB1 cannabinoid receptor, as well as the endogenous ligands of these receptors in food intake is documented. Finally, the use of opioid-cannabinoid system interactions as a new approach in the search for the next generation therapeutics controlling food intake disorders is discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据