4.6 Article

Human Umbilical Cord Mesenchymal Stem Cells for Adjuvant Treatment of a Critically III COVID-19 Patient: A Case Report

期刊

INFECTION AND DRUG RESISTANCE
卷 13, 期 -, 页码 3295-3300

出版社

DOVE MEDICAL PRESS LTD
DOI: 10.2147/IDR.S272645

关键词

COVID-19; UC-MSCs; critically ill; cell transplantation; case report

资金

  1. National Key Research and Development Program of China [2016YFA0101000, 2016YFA0101003, 2018YFA0109800, 2020YFC0844000]
  2. CAMS Innovation Fund for Medical Sciences [2017-I2M -3-007]
  3. 111 Project [B18007]

向作者/读者索取更多资源

Background: COVID-19 (coronavirus disease 2019) has become a global public health emergency since patients were first detected in Wuhan, China, in December 2019. Currently, there are no satisfying antiviral medications and vaccines available. Case Presentation: We reported the treatment process and clinical outcome of a 48-year-old man critically ill COVID-19 patient who received transfusion of allogenic human umbilical cord mesenchymal stem cells (UC-MSCs). Conclusions: We proposed that UC-MSC transfusion might be a new option for critically ill COVID-19. Although only one case we were shown, more similar clinical cases are inquired for further evidence providing the potential effectiveness of UC-MSC treatment.

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