期刊
CURRENT ORGANIC CHEMISTRY
卷 20, 期 25, 页码 2681-2689出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1385272820666160218233923
关键词
Azadirachtin A; biosafety; dengue; filariasis; limonoids; malaria; neem cake; nimbin; salannin
资金
- PROAPI [PRAF 2015]
- University of Pisa, Department of Agriculture, Food and Environment [COFIN2015_22]
- King Saud University, through Vice Deanship of Research Chairs
In the near future, a number of molecules employed in insect pest control may lose their efficacy. Pesticide resistance is an increasing problem of public health importance, and more environmental-friendly control approaches against arthropod pests of medical and veterinary relevance are urgently needed. The seed oil of neem, Azadirachta indica (Meliaceae), contains more than 100 biologically active compounds. Many formulations derived from them showed biotoxicity, antifeedancy and repellent activity against several important mosquito species, including malaria, dengue, zika and filariasis vectors. In this review, we focus on the effectiveness of neem-borne mosquitocides, with the goal to develop an ideal mosquitocide, that should be effective, eco-friendly and cheap, being preferentially derived from botanical by-products (e.g. neem cake) easily produced by countries with limited industrial facilities.
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