4.2 Article

Death Due to COVID-19 in an Infant with Combined Immunodeficiencies

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BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1871530320666201021142313

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Combined immunodeficiency; COVID-19; cardiac injury; infant; death; bone marroow

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The case of an infant with severe combined immunodeficiencies who was affected and died from COVID-19 highlights the importance of the immune system in viral infections. Understanding how the immune system affects viral infections is valuable for improving our understanding of COVID-19 presentation in immune deficient patients.
Background: Severe Acute Respiratory Syndrome Coronavirus 2 has affected millions of people, and especially in adult patients with underlying diseases lead to death. Meanwhile pediatric patients with inherited defects of T cell should be prone to viral diseases. Case Presentation: Herein, we report an infant with severe combined immunodeficiencies, who were affected and died because of COVID-19. Conclusion: Considering the importance of finding how immune system can affect the viral infection, presentation of COVID-19 in immune deficient patients can be valuable.

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