相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structural insights into the gating mechanisms of TRPV channels
Ruth A. Pumroy et al.
CELL CALCIUM (2020)
A specialized pore turret in the mammalian cation channel TRPV1 is responsible for distinct and species-specific heat activation thresholds
Guangxu Du et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Structural mechanisms underlying activation of TRPV1 channels by pungent compounds in gingers
Yue Yin et al.
BRITISH JOURNAL OF PHARMACOLOGY (2019)
Structures of TRPV2 in distinct conformations provide insight into role of the pore turret
Timothy L. Dosey et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)
The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel
Fan Yang et al.
NATURE COMMUNICATIONS (2018)
TRPV1 pore turret dictates distinct DkTx and capsaicin gating
Matan Geron et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Structure of a eukaryotic cyclic-nucleotide-gated channel
Minghui Li et al.
NATURE (2017)
Understand spiciness: mechanism of TRPV1 channel activation by capsaicin
Fan Yang et al.
PROTEIN & CELL (2017)
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K+ Channels
Marcus Schewe et al.
CELL (2016)
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
Yuan Gao et al.
NATURE (2016)
Proton block of proton-activated TRPV1 current
Bo Hyun Lee et al.
JOURNAL OF GENERAL PHYSIOLOGY (2015)
Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel
Fan Yang et al.
NATURE CHEMICAL BIOLOGY (2015)
Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain
Rebeca Caires et al.
NATURE COMMUNICATIONS (2015)
Mechanism for attenuated outward conductance induced by mutations in the cytoplasmic pore of Kir2.1 channels
Hsueh-Kai Chang et al.
SCIENTIFIC REPORTS (2015)
Divalent cations activate TRPV1 through promoting conformational change of the extracellular region
Fan Yang et al.
JOURNAL OF GENERAL PHYSIOLOGY (2014)
Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold
Xu Cao et al.
JOURNAL OF GENERAL PHYSIOLOGY (2014)
Dissecting Domain-Specific Evolutionary Pressure Profiles of Transient Receptor Potential Vanilloid Subfamily Members 1 to 4
Pau Donate-Macian et al.
PLOS ONE (2014)
High temperature sensitivity is intrinsic to voltage-gated potassium channels
Fan Yang et al.
ELIFE (2014)
TRP Channels and Pain
David Julius
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 29 (2013)
Voltage-Dependence in Thermo-Voltage Sensitive Channel TRPV1. A Delocalized Voltage Sensor?
David Baez-Nieto et al.
BIOPHYSICAL JOURNAL (2013)
The Role of Allosteric Coupling on Thermal Activation of Thermo-TRP Channels
Andres Jara-Oseguera et al.
BIOPHYSICAL JOURNAL (2013)
TRPV1 structures in distinct conformations reveal activation mechanisms
Erhu Cao et al.
NATURE (2013)
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
Maofu Liao et al.
NATURE (2013)
An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations
Ernesto Vargas et al.
JOURNAL OF GENERAL PHYSIOLOGY (2012)
Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations
Yuanyuan Cui et al.
JOURNAL OF GENERAL PHYSIOLOGY (2012)
Enhanced excitability of small dorsal root ganglion neurons in rats with bone cancer pain
Qin Zheng et al.
MOLECULAR PAIN (2012)
The biophysical and molecular basis of TRPV1 proton gating
Eduardo Aneiros et al.
EMBO JOURNAL (2011)
Kinetic and Energetic Analysis of Thermally Activated TRPV1 Channels
Jing Yao et al.
BIOPHYSICAL JOURNAL (2010)
Conserved Residues within the Putative S4-S5 Region Serve Distinct Functions among Thermosensitive Vanilloid Transient Receptor Potential (TRPV) Channels
Stepana Boukalova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Thermosensitive TRP channel pore turret is part of the temperature activation pathway
Fan Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Mutations reveal voltage gating of CNGA1 channels in saturating cGMP
Juan Ramon Martinez-Francois et al.
JOURNAL OF GENERAL PHYSIOLOGY (2009)
Voltage-sensing phosphatase: actions and potentials
Yasushi Okamura et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
How membrane proteins sense voltage
Francisco Bezanilla
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Voltage is a partial activator of rat thermosensitive TRP channels
Jose A. Matta et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment
Stephen B. Long et al.
NATURE (2007)
Thermo TRP channels as modular proteins with allosteric gating
Ramon Latorre et al.
CELL CALCIUM (2007)
Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor
Yair Ben-Chaim et al.
NATURE (2006)
Role of charged residues in the S1-S4 voltage sensor of BK channels
ZM Ma et al.
JOURNAL OF GENERAL PHYSIOLOGY (2006)
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels
T Voets et al.
NATURE (2004)
Low pH potentiates both capsaicin binding and channel Gating of VR1 receptors
SJ Ryu et al.
JOURNAL OF GENERAL PHYSIOLOGY (2003)
Coupling between voltage sensor activation, Ca2+ binding and channel opening in large conductance (BK) potassium channels
FT Horrigan et al.
JOURNAL OF GENERAL PHYSIOLOGY (2002)
Gating rearrangements in cyclic nucleotide-gated channels revealed by patch-clamp fluorometry
J Zheng et al.
NEURON (2000)
Acid potentiation of the capsaicin receptor determined by a key extracellular site
SE Jordt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)