期刊
CURRENT OPINION IN PHARMACOLOGY
卷 28, 期 -, 页码 8-13出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.coph.2016.02.009
关键词
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资金
- Arthritis Research UK [20413, 20859]
- Versus Arthritis [20859, 20413] Funding Source: researchfish
Osteoarthritis (OA) is a degenerative joint disease and the most common form of arthritis. Characterised by articular cartilage loss, subchondral bone thickening and osteophyte formation, the OA joint afflicts much pain and disability. Whilst OA has been associated with many contributing factors, its underpinning molecular mechanisms are, nevertheless, not fully understood. Clinical management of OA is largely palliative and there is an ever growing need for an effective disease modifying treatment. This review discusses some of the recent progress in OA therapies in the different joint tissues affected by OA pathology.
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