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AMPK phosphorylation of raptor mediates a metabolic checkpoint
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MOLECULAR CELL (2008)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCα but not S6K1
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S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt
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MOLECULAR CELL (2006)
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
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CELL (2006)
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s
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mTOR•RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
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SCIENCE (2005)
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
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