期刊
LIGHT-SCIENCE & APPLICATIONS
卷 9, 期 1, 页码 -出版社
SPRINGERNATURE
DOI: 10.1038/s41377-020-00375-8
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资金
- HELMHOLTZ (European Research Council (ERC)) [610110]
- ANR [ANR-10-LABX-65, ANR-11-IDEX-0004-02, ANR-18-IAHU-0001]
Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue but lacks functional information. We present dynamic full-field optical coherence tomography as a technique to noninvasively image living human induced pluripotent stem cell-derived retinal organoids. Coloured images with an endogenous contrast linked to organelle motility are generated, with submicrometre spatial resolution and millisecond temporal resolution, creating a way to identify specific cell types in living tissue via their function.
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