期刊
CURRENT OPINION IN MICROBIOLOGY
卷 30, 期 -, 页码 36-43出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2015.12.004
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资金
- Ministerio de Economia y Competitividad, Spain [BIO2011-23032, BIO2014-55075-P]
- FEDER funds
- CSIC [201440E026]
- Andalucia Talent Hub Program
- European Union's Seventh Framework Program, Marie Sklodowska-Curie actions [291780]
- Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucia
Nowadays, there is increasing interest for bacterial polysaccharides in a wide variety of industrial sectors. This is due to their chemical and reological properties, and also the possibility to be obtained by fermentation processes. Biosynthesis of a growing number of exopolysaccharides (EPS) has been reported to be regulated by the ubiquitous second messenger c-di-GMP in a limited number of bacterial species. Since most bacteria are yet unexplored, it is likely that an unsuspected number and variety of EPS structures activated by c-di-GMP await to be uncovered. In the search of new EPS, manipulation of bacterial c-di-GMP metabolism can be combined with high throughput approaches for screening of large collections of bacteria. In addition, c-di-GMP activation of EPS production and promotion of cell aggregation may have direct applications in environmental industries related with biofuel production or wastewater treatments.
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